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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Pathstone Holdings
151
Pathstone Holdings
New Jersey
$2.76M +$1.17M +2,297 +94%
PFA
152
Peak Financial Advisors
Colorado
$2.6M +$1.69M +3,312 +287%
ProShare Advisors
153
ProShare Advisors
Maryland
$2.59M +$243K +475 +12%
HF
154
HRT Financial
New York
$2.46M +$2.15M +4,218 New
PA
155
Profund Advisors
Maryland
$2.42M -$23K -45 -1%
Los Angeles Capital Management
156
Los Angeles Capital Management
California
$2.4M +$245K +479 +9%
ASRS
157
Arizona State Retirement System
Arizona
$2.35M -$110K -215 -5%
SAM
158
Shikiar Asset Management
New York
$2.33M
Acadian Asset Management
159
Acadian Asset Management
Massachusetts
$2.3M +$2.02M +3,958 New
Cetera Investment Advisers
160
Cetera Investment Advisers
Illinois
$2.3M +$110K +215 +6%
MAP
161
Moody Aldrich Partners
Massachusetts
$2.26M +$1.98M +3,876 New
DekaBank Deutsche Girozentrale
162
DekaBank Deutsche Girozentrale
Germany
$2.25M
KOCAA
163
Knights of Columbus Asset Advisors
Connecticut
$2.16M -$74.6K -146 -4%
CUAMC
164
China Universal Asset Management Company
China
$2.16M -$105K -206 -5%
CCM
165
Cinctive Capital Management
New York
$2.15M +$41.4K +81 +2%
BHCM
166
Brevan Howard Capital Management
Jersey
$2.12M +$1.15M +2,257 +164%
AF
167
Allworth Financial
California
$2.07M +$5.11K +10 +0.3%
NFSG
168
Newbridge Financial Services Group
Florida
$2.07M -$48K -94 -3%
MAM
169
Martingale Asset Management
Massachusetts
$1.97M -$577K -1,129 -25%
FCM
170
Farallon Capital Management
California
$1.93M
SO
171
STRS Ohio
Ohio
$1.92M +$562K +1,100 +50%
SFM
172
Sphera Funds Management
Israel
$1.92M +$1.69M +3,300 New
KK
173
KLP Kapitalforvaltning
Norway
$1.89M +$123K +240 +8%
Osaic Holdings
174
Osaic Holdings
Arizona
$1.78M +$1.15M +2,248 +280%
Zurich Cantonal Bank
175
Zurich Cantonal Bank
Switzerland
$1.73M +$437K +855 +40%