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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
EGM
126
Engineers Gate Manager
New York
$5.07M +$2.95M +5,774 +197%
HWAM
127
Hennion & Walsh Asset Management
New Jersey
$4.75M -$2.39M -4,684 -36%
TI
128
Trexquant Investment
Connecticut
$4.53M +$3.98M +7,784 New
IIM
129
INTECH Investment Management
Florida
$4.25M +$322K +631 +9%
Principal Financial Group
130
Principal Financial Group
Iowa
$4.23M -$2.46M -4,807 -40%
PHS
131
PFM Health Sciences
California
$4.23M +$3.71M +7,258 New
Millennium Management
132
Millennium Management
New York
$4.06M +$2.65M +5,180 +288%
ET
133
Entropy Technologies
New York
$4.04M +$1.65M +3,240 +88%
CFM
134
Capricorn Fund Managers
United Kingdom
$3.84M +$3.37M +6,600 New
Calamos Advisors
135
Calamos Advisors
Illinois
$3.82M +$1.06M +2,081 +46%
SG Americas Securities
136
SG Americas Securities
New York
$3.72M +$610K +1,195 +23%
SPS
137
Susquehanna Portfolio Strategies
Pennsylvania
$3.64M
Victory Capital Management
138
Victory Capital Management
Texas
$3.39M +$30.1K +59 +1%
FMI
139
F/M Investments
District of Columbia
$3.34M -$298K -584 -9%
Prudential Financial
140
Prudential Financial
New Jersey
$3.3M -$122K -238 -4%
Assenagon Asset Management
141
Assenagon Asset Management
Luxembourg
$3.14M +$2.75M +5,390 New
BCI
142
Brinker Capital Investments
Pennsylvania
$3.12M +$643K +1,259 +31%
Tudor Investment Corp
143
Tudor Investment Corp
Connecticut
$3.08M +$2.23M +4,359 +471%
FCM
144
Fieldview Capital Management
Michigan
$3.03M +$275K +538 +12%
Handelsbanken Fonder
145
Handelsbanken Fonder
Sweden
$2.96M +$347K +680 +15%
ONGA
146
O'Neil Global Advisors
California
$2.95M +$2.58M +5,060 New
State of New Jersey Common Pension Fund D
147
State of New Jersey Common Pension Fund D
New Jersey
$2.94M -$92.4K -181 -3%
PFSRSONJ
148
Police & Firemen's Retirement System of New Jersey
New Jersey
$2.92M -$76.1K -149 -3%
AssetMark Inc
149
AssetMark Inc
California
$2.8M -$127K -248 -5%
State Board of Administration of Florida Retirement System
150
State Board of Administration of Florida Retirement System
Florida
$2.77M +$76.6K +150 +3%