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Madrigal Pharmaceuticals

384 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 83 funds opening new positions, 136 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
384
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
13
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$323M
Puts
$271M
Net Calls
Net Calls Change

Top Buyers

1 +$87.7M
2 +$79M
3 +$74.4M
4
Lord, Abbett & Co
Lord, Abbett & Co
New Jersey
+$72.9M
5
Alkeon Capital Management
Alkeon Capital Management
New York
+$61.3M

Top Sellers

1 -$132M
2 -$102M
3 -$58.6M
4
Morgan Stanley
Morgan Stanley
New York
-$50.7M
5
AAA
Affinity Asset Advisors
New York
-$42.8M
Name Holding Trade Value Shares
Change
Change in
Stake
HWAM
126
Hennion & Walsh Asset Management
New Jersey
$4.75M
TI
127
Trexquant Investment
Connecticut
$4.53M
IIM
128
INTECH Investment Management
Florida
$4.25M
Principal Financial Group
129
Principal Financial Group
Iowa
$4.23M
PHS
130
PFM Health Sciences
California
$4.23M
Millennium Management
131
Millennium Management
New York
$4.06M
ET
132
Entropy Technologies
New York
$4.04M
CFM
133
Capricorn Fund Managers
United Kingdom
$3.84M
Calamos Advisors
134
Calamos Advisors
Illinois
$3.82M
SG Americas Securities
135
SG Americas Securities
New York
$3.72M
SPS
136
Susquehanna Portfolio Strategies
Pennsylvania
$3.64M
Victory Capital Management
137
Victory Capital Management
Texas
$3.39M
FMI
138
F/M Investments
District of Columbia
$3.34M
Prudential Financial
139
Prudential Financial
New Jersey
$3.3M
Assenagon Asset Management
140
Assenagon Asset Management
Luxembourg
$3.14M
BCI
141
Brinker Capital Investments
Pennsylvania
$3.12M
Tudor Investment Corp
142
Tudor Investment Corp
Connecticut
$3.08M
FCM
143
Fieldview Capital Management
Michigan
$3.03M
Handelsbanken Fonder
144
Handelsbanken Fonder
Sweden
$2.96M
ONGA
145
O'Neil Global Advisors
California
$2.95M
State of New Jersey Common Pension Fund D
146
State of New Jersey Common Pension Fund D
New Jersey
$2.94M
PFSRSONJ
147
Police & Firemen's Retirement System of New Jersey
New Jersey
$2.92M
AssetMark Inc
148
AssetMark Inc
California
$2.8M
State Board of Administration of Florida Retirement System
149
State Board of Administration of Florida Retirement System
Florida
$2.77M
Pathstone Holdings
150
Pathstone Holdings
New Jersey
$2.76M