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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Susquehanna International Group
51
Susquehanna International Group
Pennsylvania
$37.5M -$20.6M -40,352 -38%
VOYA Investment Management
52
VOYA Investment Management
Georgia
$37.4M +$2.46M +4,817 +8%
CS
53
Candriam SCA
Luxembourg
$37.2M +$7.12M +13,941 +28%
Connor, Clark & Lunn Investment Management (CC&L)
54
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$33.9M -$14M -27,478 -32%
JG
55
Jain Global
New York
$30.7M +$26.9M +52,721 New
Ensign Peak Advisors
56
Ensign Peak Advisors
Utah
$29.7M -$1.15M -2,257 -4%
Mirae Asset Global Investments
57
Mirae Asset Global Investments
South Korea
$29.5M +$27.1K +53 +0.1%
EAM
58
EULAV Asset Management
Florida
$28.5M -$1.02M -2,000 -4%
Russell Investments Group
59
Russell Investments Group
United Kingdom
$28M +$1.67M +3,274 +7%
Canada Pension Plan Investment Board
60
Canada Pension Plan Investment Board
Ontario, Canada
$26.9M +$19M +37,120 +412%
Wells Fargo
61
Wells Fargo
California
$25.3M +$2.88M +5,639 +15%
JP Morgan Chase
62
JP Morgan Chase
New York
$23.3M -$3.96M -7,745 -16%
Marshall Wace
63
Marshall Wace
United Kingdom
$23M +$19.9M +38,878 +5,554%
EA
64
Emerald Advisers
Pennsylvania
$22.7M -$6.04M -11,824 -23%
Barclays
65
Barclays
United Kingdom
$22.5M -$5.72M -11,192 -22%
Citadel Advisors
66
Citadel Advisors
Florida
$21M -$6.25M -12,238 -25%
ACM
67
Atika Capital Management
New York
$19.8M +$17.4M +34,000 New
SBH
68
Segall Bryant & Hamill
Illinois
$19.5M +$5.63M +11,030 +49%
GGHC
69
Gilder Gagnon Howe & Co
New York
$19.5M +$1.34M +2,620 +8%
Public Sector Pension Investment Board (PSP Investments)
70
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$19.1M +$16.8M +32,871 New
California Public Employees Retirement System
71
California Public Employees Retirement System
California
$18.2M +$3.67M +7,189 +30%
AAA
72
Affinity Asset Advisors
New York
$18.1M -$42.8M -83,869 -73%
GAM
73
Groupama Asset Management
France
$17.8M +$1.62M +3,176 +12%
Ameriprise
74
Ameriprise
Minnesota
$17.1M +$8.32M +16,290 +125%
Schroder Investment Management Group
75
Schroder Investment Management Group
United Kingdom
$17M +$6.35M +12,439 +75%