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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
JGC
401
J. Goldman & Co
New York
-$665K -1,449 Closed
BC
402
Bayforest Capital
United Kingdom
-$624K -1,360 Closed
DFCM
403
Dark Forest Capital Management
Puerto Rico
-$577K -1,259 Closed
BFM
404
Boothbay Fund Management
New York
-$512K -1,117 Closed
GIA
405
Gladstone Institutional Advisory
Florida
-$501K -1,093 Closed
PCM
406
Penserra Capital Management
California
-$437K -954 Closed
P
407
Pitcairn
Pennsylvania
-$354K -771 Closed
TCA
408
Transcend Capital Advisors
New Jersey
-$309K -673 Closed
SRL
409
Scientech Research LLC
New Jersey
-$291K -634 Closed
QIM
410
Quantitative Investment Management
Virginia
-$260K -569 Closed
I
411
InceptionR
California
-$259K -565 Closed
PWM
412
Palumbo Wealth Management
New York
-$250K -545 Closed
CCM
413
Coldstream Capital Management
Washington
-$235K -512 Closed
BWCS
414
Beirne Wealth Consulting Services
Connecticut
-$233K -508 Closed
SA
415
Sovran Advisors
California
-$214K -500 Closed
BCM
416
Bayesian Capital Management
New York
-$225K -491 Closed
JFGIW
417
Johnson Financial Group Inc (Wisconsin)
Wisconsin
-$50.5K -110 Closed
SWM
418
Spire Wealth Management
Virginia
-$45.9K -100 Closed
MG
419
Mather Group
Illinois
-$33.3K -73 Closed
PS
420
Principal Securities
Iowa
-$32.6K -71 Closed
NA
421
NewEdge Advisors
Louisiana
-$32.1K -70 Closed
RA
422
Rise Advisors
New York
-$16.1K -35 Closed
CI Investments Inc
423
CI Investments Inc
Ontario, Canada
-$12K -26 Closed
FIA
424
FNY Investment Advisers
New York
-$3K -7 Closed
JWM
425
JPL Wealth Management
Colorado
-$2.29K -5 Closed