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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Walleye Capital
326
Walleye Capital
New York
$40.2K +$35.2K +69 New
Daiwa Securities Group
327
Daiwa Securities Group
Japan
$40K -$1.02K -2 -3%
Optiver Holding
328
Optiver Holding
Netherlands
$39.6K -$34.7K -68 -50%
FHC
329
First Horizon Corporation
Tennessee
$39.6K -$3.58K -7 -9%
MCM
330
MAI Capital Management
Ohio
$39K +$31.2K +61 +1,017%
KAS
331
Kemnay Advisory Services
New York
$39K +$34.2K +67 New
APW
332
Aventura Private Wealth
Florida
$36.1K
SS
333
SBI Securities
Japan
$35.5K -$6.13K -12 -16%
QL
334
Quarry LP
New York
$32K -$15.8K -31 -36%
ME
335
McIlrath & Eck
Washington
$30.3K
CIBC Private Wealth Group
336
CIBC Private Wealth Group
Georgia
$30.3K +$511 +1 +2%
FHA
337
Flagship Harbor Advisors
Massachusetts
$29.1K +$25.5K +50 New
NS
338
NBC Securities
Alabama
$28K
BWA
339
Basecamp Wealth Advisors
Washington
$25K +$22K +43 New
CHC
340
City Holding Co
West Virginia
$23.3K +$20.4K +40 New
QA
341
Quattro Advisors
Pennsylvania
$18.1K +$15.8K +31 New
RS
342
Rakuten Securities
Japan
$17.5K
LSA
343
Leonteq Securities AG
Switzerland
$16.9K -$13.8K -27 -48%
HNB
344
Huntington National Bank
Ohio
$16.9K -$511 -1 -3%
BCPWM
345
Bradley & Co Private Wealth Management
Florida
$15.7K
AAP
346
Arax Advisory Partners
Colorado
$15.7K +$6.13K +12 +80%
Bessemer Group
347
Bessemer Group
New Jersey
$14K +$9.7K +19 +380%
CLOS
348
Compagnie Lombard Odier SCmA
Switzerland
$14K -$40.9K -80 -77%
RIL
349
Rothschild Investment LLC
Illinois
$14K
CIM
350
Contravisory Investment Management
Massachusetts
$13.4K +$11.7K +23 New