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Madrigal Pharmaceuticals
MDGL

352 hedge funds and large institutions have $10.7B invested in Madrigal Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 87 funds opening new positions, 107 increasing their positions, 107 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

135% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 37

50% more capital invested

Capital invested by funds: $7.13B → $10.7B (+$3.6B)

27% more call options, than puts

Call options by funds: $326M | Put options by funds: $258M

17% more funds holding in top 10

Funds holding in top 10: 12 → 14 (+2)

15% more funds holding

Funds holding: 305 → 352 (+47)

0% more repeat investments, than reductions

Existing positions increased: 107 | Existing positions reduced: 107

0.74% less ownership

Funds ownership: 106.08% → 105.34% (-0.74%)

Holders
352
Holders Change
+47
Holders Change %
+15.41%
% of All Funds
4.62%
Holding in Top 10
14
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+16.67%
% of All Funds
0.18%
New
87
Increased
107
Reduced
107
Closed
37
Calls
$326M
Puts
$258M
Net Calls
+$68.8M
Net Calls Change
-$69.9M

Top Buyers

1
Wellington Management Group
Wellington Management Group
Massachusetts
+$148M
2
Goldman Sachs
Goldman Sachs
New York
+$73.2M
3
BBA
Baker Bros. Advisors
New York
+$61.8M
4
BlackRock
BlackRock
New York
+$45.1M
5
Alkeon Capital Management
Alkeon Capital Management
New York
+$44.8M

Top Sellers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$130M
2
UBS Group
UBS Group
Switzerland
-$108M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$107M
4
PC
Paulson & Co
New York
-$67.9M
5
Citadel Advisors
Citadel Advisors
Florida
-$59.3M
Name Holding Trade Value Shares
Change 		Change in
Stake
VWWMG
326
Vermillion & White Wealth Management Group
Pennsylvania
$6.42K – – –
SPIA
327
Steward Partners Investment Advisory
New York
$5.5K +$4.1K +11 +1,100%
MPWT
328
MassMutual Private Wealth & Trust
Connecticut
$4.59K – – –
PFBT
329
Parkside Financial Bank & Trust
Missouri
$4.59K +$746 +2 +25%
CIA
330
Cape Investment Advisory
Georgia
$4.13K – – –
WTC
331
WhitTier Trust Company
Nevada
$3.99K – – –
MAM
332
Meeder Asset Management
Ohio
$3.21K +$2.61K +7 New
SRCM
333
Signature Resources Capital Management
California
$3.21K +$2.61K +7 New
FIA
334
FNY Investment Advisers
New York
$3K +$2.61K +7 New
MCM
335
MAI Capital Management
Ohio
$2.75K -$2.24K -6 -50%
WB
336
Webster Bank
Connecticut
$2.75K – – –
BIA
337
Bell Investment Advisors
California
$2.29K – – –
JWM
338
JPL Wealth Management
Colorado
$2.29K +$1.86K +5 New
BBHC
339
Brown Brothers Harriman & Co
New York
$2.29K – – –
Bessemer Group
340
Bessemer Group
New Jersey
$2K – – –
EWA
341
EverSource Wealth Advisors
Alabama
$1.83K – – –
PPC
342
Park Place Capital
Alabama
$1.83K – – –
RWS
343
Retirement Wealth Solutions
Wisconsin
$1.83K +$1.49K +4 New
TIM
344
Tortoise Investment Management
New York
$1.38K +$373 +1 +50%
MAM
345
Marquette Asset Management
Minnesota
$1.38K +$1.12K +3 New
SC
346
SouthState Corp
Florida
$918 – – –
CJ
347
Caitlin John
Michigan
$917 +$746 +2 New
TFA
348
Transamerica Financial Advisors
Florida
$917 +$746 +2 New
FFO
349
Fortitude Family Office
Arizona
$459 – – –
TCM
350
TD Capital Management
Tennessee
$459 – – –
12 13
14
15 16

MDGL Hedge Fund Activity: Q3 2025 in Review

352 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Madrigal Pharmaceuticals (MDGL) for Q3 2025, worth a combined $10.7B — up 50% from $7.13B a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new MDGL positions and 37 closed out — a net gain of 50 holders — while 107 added to existing stakes and 107 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $148M. The largest seller was Janus Henderson Group, cutting an estimated $130M.

  • 352 institutional investors held Madrigal Pharmaceuticals (MDGL) as of Q3 2025, up from 305 in Q2 2025.
  • Funds reported $10.7B of Madrigal Pharmaceuticals stock for Q3 2025, up 50% quarter-over-quarter.
  • 87 funds opened new Madrigal Pharmaceuticals positions in Q3 2025 and 37 closed out, a net change of +50 holders.
  • The largest Madrigal Pharmaceuticals buyer in Q3 2025 was Wellington Management Group, an estimated $148M added.
  • The largest Madrigal Pharmaceuticals seller in Q3 2025 was Janus Henderson Group, an estimated $130M sold.

Based on aggregated 13F filings for Q3 2025.