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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
VEA
301
Virtus ETF Advisers
New York
$210K +$184K +360 New
SAM
302
Sectoral Asset Management
Quebec, Canada
$205K -$193K -378 -52%
DWM
303
Destination Wealth Management
California
$204K +$179K +350 New
C
304
Covestor
United Kingdom
$180K +$137K +268 +654%
PNC Financial Services Group
305
PNC Financial Services Group
Pennsylvania
$161K +$7.66K +15 +6%
PA
306
Parallel Advisors
California
$146K -$4.09K -8 -3%
PWPS
307
Pinnacle Wealth Planning Services
Ohio
$136K +$119K +233 New
UB
308
UMB Bank
Missouri
$134K
Walleye Trading
309
Walleye Trading
New York
$125K +$109K +214 New
DB
310
Danske Bank
Denmark
$116K +$102K +200 New
Jones Financial Companies
311
Jones Financial Companies
Missouri
$116K
MA
312
Montag & Associates
Georgia
$113K
SAM
313
Smartleaf Asset Management
Massachusetts
$109K +$32.2K +63 +51%
VNA
314
Valley National Advisers
Pennsylvania
$93K +$62.3K +122 +313%
TM
315
Torren Management
California
$90.3K +$79.2K +155 New
FFA
316
Farther Finance Advisors
California
$81.5K +$18.4K +36 +35%
GI
317
GAMMA Investing
California
$80.4K +$24.5K +48 +53%
SCM
318
Sterling Capital Management
North Carolina
$71K +$39.3K +77 +171%
S
319
SignatureFD
Georgia
$67K
SAG
320
SageView Advisory Group
California
$65.2K +$57.2K +112 New
ACM
321
Accent Capital Management
Ohio
$54.7K +$18.9K +37 +65%
EB
322
Eastern Bank
Massachusetts
$50.1K +$10.7K +21 +32%
GRP
323
Global Retirement Partners
California
$47.8K +$4.09K +8 +11%
CA
324
CoreCap Advisors
Michigan
$47.8K +$7.15K +14 +21%
PEAK6
325
PEAK6
Illinois
$44.9K +$39.3K +77 New