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Madrigal Pharmaceuticals
MDGL

Overview Fund Activity

303 hedge funds and large institutions have $7.13B invested in Madrigal Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 40 funds opening new positions, 105 increasing their positions, 109 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
303
Holders Change
-15
Holders Change %
-4.72%
% of All Funds
4.06%
Holding in Top 10
12
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.16%
New
40
Increased
105
Reduced
109
Closed
52
Calls
$294M
Puts
$155M
Net Calls
+$139M
Net Calls Change
-$43.4M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
$62.7M
2
Vanguard Group
Vanguard Group
Pennsylvania
$568M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
$114M
4
UBS Group
UBS Group
Switzerland
$153M
5
PCH
Polar Capital Holdings
United Kingdom
$68.2M

Top Sellers

1
Holocene Advisors
Holocene Advisors
New York
$0
2
Fidelity Investments
Fidelity Investments
Massachusetts
$135M
3
WP
Woodline Partners
California
$48.3M
4
ACA
Avoro Capital Advisors
New York
$567M
5
Morgan Stanley
Morgan Stanley
New York
$75M
Name Holding Trade Value Shares
Change 		Shares
Change %
SPIA
301
Steward Partners Investment Advisory
New York
$303 – – –
FFO
302
Fortitude Family Office
Arizona
$303 – – –
BTI
303
Blue Trust Inc
Georgia
$303 +$303 +1 New
Holocene Advisors
304
Holocene Advisors
New York
– -$129M -390,545 Closed
Federated Hermes
305
Federated Hermes
Pennsylvania
– -$19.2M -58,025 Closed
Jane Street
306
Jane Street
New York
– -$17.2M -51,890 Closed
PA
307
Perceptive Advisors
New York
– -$15.4M -46,500 Closed
PBM
308
Propel Bio Management
California
– -$9.95M -30,032 Closed
CCM
309
Cutter Capital Management
New York
– -$7.95M -24,000 Closed
CSS
310
Cubist Systematic Strategies
Connecticut
– -$6.57M -19,827 Closed
SAM
311
Simplify Asset Management
Nevada
– -$5.4M -16,302 Closed
EI
312
EAM Investors
California
– -$4.82M -14,557 Closed
Hudson Bay Capital Management
313
Hudson Bay Capital Management
Connecticut
– -$4.18M -12,610 Closed
CM
314
Castleark Management
Illinois
– -$3.5M -10,580 Closed
SCM
315
Silverarc Capital Management
Massachusetts
– -$3.43M -10,344 Closed
CF
316
Corebridge Financial
Texas
– -$2.92M -8,807 Closed
SSA
317
Schonfeld Strategic Advisors
New York
– -$1.85M -5,580 Closed
SCM
318
Superstring Capital Management
New York
– -$1.26M -3,815 Closed
CCA
319
Carrera Capital Advisors
Michigan
– -$1.24M -3,749 Closed
QCM
320
Quantinno Capital Management
New York
– -$876K -2,644 Closed
CPA
321
Capital Performance Advisors
California
– -$802K -2,422 Closed
ACM
322
Aster Capital Management
United Arab Emirates
– -$748K -2,191 Closed
SC
323
SummitTX Capital
Texas
– -$607K -1,833 Closed
Nomura Holdings
324
Nomura Holdings
Japan
– -$560K -1,692 Closed
SP
325
SIH Partners
Delaware
– -$461K -1,391 Closed
11 12
13
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