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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
OIA
276
OneDigital Investment Advisors
Kansas
$302K -$49.5K -97 -16%
TWA
277
TCI Wealth Advisors
Arizona
$301K
P
278
&Partners
Tennessee
$296K +$260K +509 New
SCM
279
Soleus Capital Management
Connecticut
$291K -$34.6M -67,836 -99%
IA
280
IFP Advisors
Florida
$268K +$46K +90 +24%
GFM
281
GF Fund Management
China
$259K -$17.9K -35 -7%
KIM
282
Kestra Investment Management
Texas
$259K +$1.53K +3 +0.7%
US Bancorp
283
US Bancorp
Minnesota
$257K +$27.1K +53 +14%
Amundi
284
Amundi
France
$254K +$223K +437 New
SC
285
SummitTX Capital
Texas
$252K +$221K +433 New
BIG
286
Brooklyn Investment Group
New York
$252K +$218K +427 New
PCM
287
Prelude Capital Management
New York
$250K +$220K +430 New
LWCFA
288
Loring Wolcott & Coolidge Fiduciary Advisors
Massachusetts
$250K
Nisa Investment Advisors
289
Nisa Investment Advisors
Missouri
$250K -$3.06K -6 -1%
EI
290
Ethic Inc
New York
$248K +$218K +426 New
A
291
AlphaQuest
New York
$245K +$188K +368 +708%
WT
292
Washington Trust
Rhode Island
$245K +$215K +420 New
KBC Group
293
KBC Group
Belgium
$241K
BC
294
Bridgefront Capital
Texas
$229K -$165K -323 -45%
OC
295
Oppenheimer & Co
New York
$228K +$200K +392 New
CL
296
Choreo LLC
Illinois
$222K +$195K +381 New
KA
297
Kozak & Associates
Colorado
$218K
AIP
298
Arrowpoint Investment Partners
Singapore
$216K -$215K -421 -53%
CFO
299
Callan Family Office
Pennsylvania
$213K +$187K +366 New
QCM
300
Quantinno Capital Management
New York
$212K +$186K +364 New