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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
VRS
251
Virginia Retirement Systems
Virginia
$466K +$409K +800 New
CPIG
252
Chicago Partners Investment Group
Illinois
$462K -$32.7K -64 -6%
VT
253
Vise Technologies
New York
$448K +$393K +769 New
DWT
254
Dorsey & Whitney Trust
South Dakota
$438K
Comerica Bank
255
Comerica Bank
Texas
$433K -$8.17K -16 -2%
ECSS
256
Eurizon Capital SGR SpA
$425K +$372K +729 New
AHL
257
Abel Hall LLC
Louisiana
$413K +$61.3K +120 +20%
CF
258
Centaurus Financial
California
$413K
MMA
259
Miracle Mile Advisors
California
$409K
CGIM
260
Cannon Global Investment Management
Florida
$408K -$51.1K -100 -13%
GT
261
Glenmede Trust
Pennsylvania
$402K +$353K +691 New
SLAM
262
Swiss Life Asset Management
$402K +$22.5K +44 +7%
ASN
263
Advisory Services Network
Georgia
$383K +$336K +658 New
Allspring Global Investments
264
Allspring Global Investments
North Carolina
$375K +$322K +631 New
M&T Bank
265
M&T Bank
New York
$366K +$321K +629 New
CSP
266
Cary Street Partners
Virginia
$366K +$321K +628 New
JGGDR
267
JGP Global Gestao de Recursos
Brazil
$364K -$213K -417 -40%
TRCT
268
Tower Research Capital (TRC)
New York
$356K +$130K +255 +71%
EWA
269
EP Wealth Advisors
California
$355K +$311K +609 New
AB
270
Amalgamated Bank
New York
$340K -$9.7K -19 -3%
Truist Financial
271
Truist Financial
North Carolina
$331K -$17.4K -34 -6%
IIC
272
Integrated Investment Consultants
Michigan
$330K
ECM
273
Everence Capital Management
Indiana
$314K
PAG
274
Private Advisor Group
New Jersey
$312K +$274K +536 New
JJBC
275
James J. Burns & Company
New York
$310K +$272K +532 New