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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
HighTower Advisors
226
HighTower Advisors
Illinois
$683K +$23.5K +46 +4%
EFG
227
Everhart Financial Group
Ohio
$677K +$360K +704 +153%
VAM
228
Verity Asset Management
North Carolina
$674K -$52.1K -102 -8%
CAPTRUST Financial Advisors
229
CAPTRUST Financial Advisors
North Carolina
$659K +$289K +565 +100%
HSBC Holdings
230
HSBC Holdings
United Kingdom
$646K +$562K +1,100 New
LCM
231
Landscape Capital Management
New Jersey
$634K +$39.8K +78 +8%
P8IP
232
Pier 88 Investment Partners
California
$629K +$552K +1,080 New
GCM
233
Graham Capital Management
Connecticut
$618K +$542K +1,062 New
N
234
Natixis
France
$606K +$532K +1,041 New
CG
235
Cynosure Group
Utah
$597K +$524K +1,025 New
William Blair & Company
236
William Blair & Company
Illinois
$582K
OF
237
Optimize Financial
California
$578K +$6.13K +12 +1%
AI
238
Atria Investments
North Carolina
$575K -$11.2K -22 -2%
SC
239
Syon Capital
California
$562K
BBA
240
Baader Bank Aktiengesellschaft
Germany
$525K -$528K -1,033 -53%
ACM
241
ADAR1 Capital Management
Texas
$521K -$2.04M -4,000 -82%
PR
242
PSP Research
Pennsylvania
$519K +$456K +892 New
PAS
243
Park Avenue Securities
New York
$499K +$36.8K +72 +9%
IB
244
Intrust Bank
Kansas
$494K +$88.9K +174 +26%
IA
245
IFG Advisory
Georgia
$491K +$431K +844 New
QCM
246
QRG Capital Management
Illinois
$486K +$32.2K +63 +8%
MYIA
247
Mount Yale Investment Advisors
Colorado
$480K +$421K +824 New
CIBC Asset Management
248
CIBC Asset Management
Ontario, Canada
$475K +$97K +190 +30%
PA
249
PharVision Advisers
Florida
$473K +$118K +231 +40%
VAS
250
Vestmark Advisory Solutions
Massachusetts
$469K +$412K +806 New