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Madrigal Pharmaceuticals

385 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 83 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
385
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
13
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$323M
Puts
$271M
Net Calls
Net Calls Change

Top Buyers

1 +$87.7M
2 +$79M
3 +$74.4M
4
Lord, Abbett & Co
Lord, Abbett & Co
New Jersey
+$72.9M
5
Alkeon Capital Management
Alkeon Capital Management
New York
+$61.3M

Top Sellers

1 -$132M
2 -$102M
3 -$58.6M
4
Morgan Stanley
Morgan Stanley
New York
-$50.7M
5
AAA
Affinity Asset Advisors
New York
-$42.8M
Name Holding Trade Value Shares
Change
Change in
Stake
HighTower Advisors
226
HighTower Advisors
Illinois
$683K
EFG
227
Everhart Financial Group
Ohio
$677K
VAM
228
Verity Asset Management
North Carolina
$674K
CAPTRUST Financial Advisors
229
CAPTRUST Financial Advisors
North Carolina
$659K
LCM
230
Landscape Capital Management
New Jersey
$634K
P8IP
231
Pier 88 Investment Partners
California
$629K
GCM
232
Graham Capital Management
Connecticut
$618K
N
233
Natixis
France
$606K
CG
234
Cynosure Group
Utah
$597K
William Blair & Company
235
William Blair & Company
Illinois
$582K
OF
236
Optimize Financial
California
$578K
AI
237
Atria Investments
North Carolina
$575K
SC
238
Syon Capital
California
$562K
BBA
239
Baader Bank Aktiengesellschaft
Germany
$525K
ACM
240
ADAR1 Capital Management
Texas
$521K
PR
241
PSP Research
Pennsylvania
$519K
PAS
242
Park Avenue Securities
New York
$499K
IB
243
Intrust Bank
Kansas
$494K
IA
244
IFG Advisory
Georgia
$491K
QCM
245
QRG Capital Management
Illinois
$486K
MYIA
246
Mount Yale Investment Advisors
Colorado
$480K
CIBC Asset Management
247
CIBC Asset Management
Ontario, Canada
$475K
PA
248
PharVision Advisers
Florida
$473K
VAS
249
Vestmark Advisory Solutions
Massachusetts
$469K
VRS
250
Virginia Retirement Systems
Virginia
$466K