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Lyra Therapeutics

30 hedge funds and large institutions have $4.42M invested in Lyra Therapeutics in 2025 Q2 according to their latest regulatory filings, with 8 funds opening new positions, 2 increasing their positions, 20 reducing their positions, and 34 closing their positions.

Holders
30
Holders Change
-27
Holders Change %
-47.37%
% of All Funds
0.4%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
%
% of All Funds
0.01%
New
8
Increased
2
Reduced
20
Closed
34
Calls
Puts
Net Calls
Net Calls Change
Name Market Value Shares Shares
Change
Shares
Change %
PA
1
Perceptive Advisors
New York
$2.29M 255,150 -12,502,412 -98%
SM
2
Sabby Management
Florida
$1.13M 125,729 +125,729 New
Vanguard Group
3
Vanguard Group
Pennsylvania
$261K 29,178 -1,736,407 -98%
Bank of America
4
Bank of America
North Carolina
$256K 28,542 +7,190 +34%
IC
5
Ikarian Capital
Texas
$190K 21,161 -1,036,987 -98%
Geode Capital Management
6
Geode Capital Management
Massachusetts
$98.5K 10,986 -1,005,018 -99%
State of Wisconsin Investment Board
7
State of Wisconsin Investment Board
Wisconsin
$94.1K 10,500 +10,500 New
Morgan Stanley
8
Morgan Stanley
New York
$19.4K 2,164 -63,455 -97%
Fidelity Investments
9
Fidelity Investments
Massachusetts
$15.7K 1,748 -56,465 -97%
BlackRock
10
BlackRock
New York
$15.1K 1,690 -3,017,296 -100%
Russell Investments Group
11
Russell Investments Group
United Kingdom
$14.3K 1,594 +1,594 New
TRCT
12
Tower Research Capital (TRC)
New York
$13.3K 1,483 -51,253 -97%
Royal Bank of Canada
13
Royal Bank of Canada
Ontario, Canada
$10K 1,102 -6,917 -86%
Citigroup
14
Citigroup
New York
$7.12K 795 -34,382 -98%
VNA
15
Valley National Advisers
Pennsylvania
$4K 500 +500 New
SRCM
16
Signature Resources Capital Management
California
$3.58K 400 +400 New
EWA
17
EverSource Wealth Advisors
Alabama
$3.21K 358 +15 +4%
Carson Wealth (CWM LLC)
18
Carson Wealth (CWM LLC)
Nebraska
$2K 202 -6,475 -97%
JPMorgan Chase & Co
19
JPMorgan Chase & Co
New York
$1.72K 192 -56,085 -100%
SS
20
SBI Securities
Japan
$762 85 -4,187 -98%
Wells Fargo
21
Wells Fargo
California
$349 39 -25,266 -100%
BNP Paribas Financial Markets
22
BNP Paribas Financial Markets
France
$224 25 -242,521 -100%
Comerica Bank
23
Comerica Bank
Texas
$206 23 -1,136 -98%
PS
24
Principal Securities
Iowa
$170 19 +19 New
Jones Financial Companies
25
Jones Financial Companies
Missouri
$91 10 -490 -98%