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Lyell Immunopharma
LYEL

Overview Fund Activity

69 hedge funds and large institutions have $81.9M invested in Lyell Immunopharma in 2025 Q2 according to their latest regulatory filings, with 10 funds opening new positions, 1 increasing their positions, 58 reducing their positions, and 52 closing their positions.

Holders
69
Holders Change
-44
Holders Change %
-38.94%
% of All Funds
0.93%
Holding in Top 10
7
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+16.67%
% of All Funds
0.09%
New
10
Increased
1
Reduced
58
Closed
52
Calls
$45K
Puts
$165K
Net Calls
-$120K
Net Calls Change
-$119K

Top Buyers

1
AVM
1
Arch Venture Management
Illinois
$16.1M
2
RC
2
RBF Capital
California
$884K
3
WP
3
Woodline Partners
California
$870K
4
O
4
OrbiMed
New York
$457K
5
Walleye Capital
5
Walleye Capital
New York
$258K

Top Sellers

1
MM
1
MWG Management
British Virgin Islands
$8.91M
2
FCMI
2
Foresite Capital Management IV
California
$7.08M
3
OPL
3
Orland Properties Ltd
British Virgin Islands
$6.67M
4
BlackRock
4
BlackRock
New York
$1.28M
5
DC
5
Decheng Capital
California
$5.26M
Name Market Value Shares Shares
Change 		Shares
Change %
Squarepoint
76
Squarepoint
New York
– – -198,324 Closed
AQR Capital Management
77
AQR Capital Management
Connecticut
– – -174,279 Closed
BP
78
BBR Partners
New York
– – -164,041 Closed
IIM
79
INTECH Investment Management
Florida
– – -124,696 Closed
Tudor Investment Corp
80
Tudor Investment Corp
Connecticut
– – -124,320 Closed
Deutsche Bank
81
Deutsche Bank
Germany
– – -82,441 Closed
CF
82
Corebridge Financial
Texas
– – -78,727 Closed
D.E. Shaw & Co
83
D.E. Shaw & Co
New York
– – -77,178 Closed
SG Americas Securities
84
SG Americas Securities
New York
– – -71,881 Closed
Jane Street
85
Jane Street
New York
– – -64,241 Closed
GCM
86
Graham Capital Management
Connecticut
– – -61,609 Closed
SEI Investments
87
SEI Investments
Pennsylvania
– – -55,900 Closed
New York State Common Retirement Fund
88
New York State Common Retirement Fund
New York
– – -51,263 Closed
VOYA Investment Management
89
VOYA Investment Management
Georgia
– – -50,329 Closed
State Board of Administration of Florida Retirement System
90
State Board of Administration of Florida Retirement System
Florida
– – -49,523 Closed
Prudential Financial
91
Prudential Financial
New Jersey
– – -48,057 Closed
ProShare Advisors
92
ProShare Advisors
Maryland
– – -47,966 Closed
CWM
93
CIBC World Markets
New York
– – -35,658 Closed
PFSRSONJ
94
Police & Firemen's Retirement System of New Jersey
New Jersey
– – -35,001 Closed
Ohio Public Employees Retirement System (OPERS)
95
Ohio Public Employees Retirement System (OPERS)
Ohio
– – -34,307 Closed
VPIM
96
Vanguard Personalized Indexing Management
California
– – -32,887 Closed
AWM
97
AE Wealth Management
Kansas
– – -25,000 Closed
Royal Bank of Canada
98
Royal Bank of Canada
Ontario, Canada
$0 25 -19,721 -100%
HSBC Holdings
99
HSBC Holdings
United Kingdom
– – -18,721 Closed
AIP
100
Ameritas Investment Partners
Nebraska
– – -17,114 Closed
1 2 3
4
5