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Lyell Immunopharma
LYEL

74 hedge funds and large institutions have $251M invested in Lyell Immunopharma in 2026 Q1 according to their latest regulatory filings, with 18 funds opening new positions, 24 increasing their positions, 8 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 8

100% more first-time investments, than exits

New positions opened: 18 | Existing positions closed: 9

37% more call options, than puts

Call options by funds: $261K | Put options by funds: $191K

9% more funds holding

Funds holding: 68 → 74 (+6)

2.6% less ownership

Funds ownership: 56.95% → 54.35% (-2.6%)

11% less funds holding in top 10

Funds holding in top 10: 9 → 8 (-1)

32% less capital invested

Capital invested by funds: $372M → $251M (-$121M)

Holders
74
Holders Change
+6
Holders Change %
+8.82%
% of All Funds
0.91%
Holding in Top 10
8
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-11.11%
% of All Funds
0.1%
New
18
Increased
24
Reduced
8
Closed
9
Calls
$261K
Puts
$191K
Net Calls
+$70K
Net Calls Change
+$1.18M

Top Buyers

1
AVM
Arch Venture Management
Illinois
+$11.4M
2
Millennium Management
Millennium Management
New York
+$9.36M
3
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$3.72M
4
VCIM
Velan Capital Investment Management
Georgia
+$2.38M
5
OM
Opaleye Management
Massachusetts
+$1.85M

Top Sellers

1
Invesco
Invesco
Georgia
-$3.04M
2
JJ
Johnson & Johnson
New Jersey
-$1.69M
3
RC
RBF Capital
California
-$713K
4
Barclays
Barclays
United Kingdom
-$334K
5
BFM
Boothbay Fund Management
New York
-$293K
Name Holding Trade Value Shares
Change 		Change in
Stake
JJ
76
Johnson & Johnson
New Jersey
– -$1.69M -54,887 Closed
BFM
77
Boothbay Fund Management
New York
– -$293K -9,516 Closed
ECM
78
ExodusPoint Capital Management
New York
– -$262K -8,511 Closed
Raymond James Financial
79
Raymond James Financial
Florida
– -$243K -7,900 Closed
CS
80
Candriam SCA
Luxembourg
– -$234K -7,617 Closed
BP
81
BBR Partners
New York
– -$210K -6,834 Closed
Acadian Asset Management
82
Acadian Asset Management
Massachusetts
– -$51K -1,657 Closed
Daiwa Securities Group
83
Daiwa Securities Group
Japan
– -$1K -45 Closed
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