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Lyell Immunopharma
LYEL

Overview Fund Activity

69 hedge funds and large institutions have $81.9M invested in Lyell Immunopharma in 2025 Q2 according to their latest regulatory filings, with 10 funds opening new positions, 1 increasing their positions, 58 reducing their positions, and 52 closing their positions.

Holders
69
Holders Change
-44
Holders Change %
-38.94%
% of All Funds
0.93%
Holding in Top 10
7
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+16.67%
% of All Funds
0.09%
New
10
Increased
1
Reduced
58
Closed
52
Calls
$45K
Puts
$165K
Net Calls
-$120K
Net Calls Change
-$119K

Top Buyers

1
AVM
1
Arch Venture Management
Illinois
$16.1M
2
RC
2
RBF Capital
California
$884K
3
WP
3
Woodline Partners
California
$870K
4
O
4
OrbiMed
New York
$457K
5
Walleye Capital
5
Walleye Capital
New York
$258K

Top Sellers

1
MM
1
MWG Management
British Virgin Islands
$8.91M
2
FCMI
2
Foresite Capital Management IV
California
$7.08M
3
OPL
3
Orland Properties Ltd
British Virgin Islands
$6.67M
4
BlackRock
4
BlackRock
New York
$1.28M
5
DC
5
Decheng Capital
California
$5.26M
Name Market Value Shares Shares
Change 		Shares
Change %
AVM
1
Arch Venture Management
Illinois
$16.1M 1,820,634 +1,820,634 New
MM
2
MWG Management
British Virgin Islands
$8.91M 1,008,116 -19,154,216 -95%
FCMI
3
Foresite Capital Management IV
California
$7.08M 800,399 -15,207,600 -95%
OPL
4
Orland Properties Ltd
British Virgin Islands
$6.67M 754,698 -14,339,271 -95%
DC
5
Decheng Capital
California
$5.26M 595,466 -11,313,875 -95%
AC
6
Almitas Capital
California
$5.13M 579,997 -1,902,609 -77%
VP
7
venBio Partners
California
$4.19M 473,479 -6,628,711 -93%
Vanguard Group
8
Vanguard Group
Pennsylvania
$3.91M 442,626 -9,295,103 -95%
FCMV
9
Foresite Capital Management V
California
$3.59M 406,652 -7,726,395 -95%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$2.71M 306,059 -6,172,777 -95%
AI
11
Alphabet Inc
California
$2.59M 293,256 -5,571,869 -95%
Citadel Advisors
12
Citadel Advisors
Florida
$2.4M 271,283 -4,235,574 -94%
HH
13
HSG Holding
Hong Kong
$1.35M 152,299 -2,893,698 -95%
BlackRock
14
BlackRock
New York
$1.28M 144,859 -12,576,712 -99%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$913K 103,270 -4,295,869 -98%
RC
16
RBF Capital
California
$884K 100,000 +100,000 New
WP
17
Woodline Partners
California
$870K 98,425 +98,425 New
MCMU
18
MIC Capital Management (UK)
United Kingdom
$769K 87,028 -1,653,541 -95%
Renaissance Technologies
19
Renaissance Technologies
New York
$594K 67,190 -1,701,310 -96%
Charles Schwab
20
Charles Schwab
California
$544K 61,503 -1,543,173 -96%
Millennium Management
21
Millennium Management
New York
$462K 52,229 +9,272 +22%
O
22
OrbiMed
New York
$457K 51,727 +51,727 New
TD Asset Management
23
TD Asset Management
Ontario, Canada
$444K 50,232 -954,410 -95%
IC
24
Ikarian Capital
Texas
$387K 43,799 -832,238 -95%
JJ
25
Johnson & Johnson
New Jersey
$368K 41,165 -782,152 -95%
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