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Lyell Immunopharma

74 hedge funds and large institutions have $251M invested in Lyell Immunopharma in 2026 Q1 according to their latest regulatory filings, with 18 funds opening new positions, 24 increasing their positions, 8 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 8

100% more first-time investments, than exits

New positions opened: 18 | Existing positions closed: 9

37% more call options, than puts

Call options by funds: $261K | Put options by funds: $191K

9% more funds holding

Funds holding: 6874 (+6)

2.6% less ownership

Funds ownership: 56.95%54.35% (-2.6%)

11% less funds holding in top 10

Funds holding in top 10: 98 (-1)

32% less capital invested

Capital invested by funds: $372M → $251M (-$121M)

Holders
74
Holders Change
+6
Holders Change %
+8.82%
% of All Funds
0.91%
Holding in Top 10
8
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-11.11%
% of All Funds
0.1%
New
18
Increased
24
Reduced
8
Closed
9
Calls
$261K
Puts
$191K
Net Calls
+$70K
Net Calls Change
+$1.18M
Name Holding Trade Value Shares
Change
Change in
Stake
AVM
1
Arch Venture Management
Illinois
$65.1M +$11.4M +488,090 +18%
GP
2
GSK plc
$30.3M
FCMI
3
Foresite Capital Management IV
California
$16.1M
OPL
4
Orland Properties Ltd
British Virgin Islands
$15.1M
VCM
5
Vanguard Capital Management
Pennsylvania
$14.4M +$16.8M +718,155 New
DC
6
Decheng Capital
California
$13.9M
AC
7
Almitas Capital
California
$11.6M
FCMV
8
Foresite Capital Management V
California
$9.57M
Millennium Management
9
Millennium Management
New York
$9.21M +$9.36M +400,254 +682%
Citadel Advisors
10
Citadel Advisors
Florida
$7.65M +$1.33M +56,761 +17%
VP
11
venBio Partners
California
$6.77M
Susquehanna International Group
12
Susquehanna International Group
Pennsylvania
$6.22M +$3.72M +159,182 +105%
AI
13
Alphabet Inc
California
$5.88M
BlackRock
14
BlackRock
New York
$3.85M +$233K +9,983 +5%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$3.35M +$93.1K +3,983 +2%
Marshall Wace
16
Marshall Wace
United Kingdom
$2.98M +$1.76M +75,201 +103%
Renaissance Technologies
17
Renaissance Technologies
New York
$2.34M +$1.8M +76,921 +195%
Goldman Sachs
18
Goldman Sachs
New York
$2.3M +$416K +17,816 +18%
VCIM
19
Velan Capital Investment Management
Georgia
$2.05M +$2.38M +102,000 New
MCMU
20
MIC Capital Management (UK)
United Kingdom
$1.75M
VFT
21
Vanguard Fiduciary Trust
Pennsylvania
$1.74M +$2.03M +86,925 New
Charles Schwab
22
Charles Schwab
California
$1.72M +$12.8K +548 +0.6%
OM
23
Opaleye Management
Massachusetts
$1.59M +$1.85M +79,097 New
State Street
24
State Street
Massachusetts
$1.45M +$492K +21,050 +41%
Jane Street
25
Jane Street
New York
$1.28M +$1.2M +51,484 +415%