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Lyell Immunopharma
LYEL

Overview Fund Activity

69 hedge funds and large institutions have $81.9M invested in Lyell Immunopharma in 2025 Q2 according to their latest regulatory filings, with 10 funds opening new positions, 1 increasing their positions, 58 reducing their positions, and 52 closing their positions.

Holders
69
Holders Change
-44
Holders Change %
-38.94%
% of All Funds
0.93%
Holding in Top 10
7
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+16.67%
% of All Funds
0.09%
New
10
Increased
1
Reduced
58
Closed
52
Calls
$45K
Puts
$165K
Net Calls
-$120K
Net Calls Change
-$119K

Top Buyers

1
AVM
1
Arch Venture Management
Illinois
$16.1M
2
RC
2
RBF Capital
California
$884K
3
WP
3
Woodline Partners
California
$870K
4
O
4
OrbiMed
New York
$457K
5
Walleye Capital
5
Walleye Capital
New York
$258K

Top Sellers

1
MM
1
MWG Management
British Virgin Islands
$8.91M
2
FCMI
2
Foresite Capital Management IV
California
$7.08M
3
OPL
3
Orland Properties Ltd
British Virgin Islands
$6.67M
4
BlackRock
4
BlackRock
New York
$1.28M
5
DC
5
Decheng Capital
California
$5.26M
Name Market Value Shares Shares
Change 		Shares
Change %
TPC
26
Takeda Pharmaceutical Company
Japan
$364K 41,165 -782,152 -95%
Jacobs Levy Equity Management
27
Jacobs Levy Equity Management
New Jersey
$350K 39,621 -519,358 -93%
State Street
28
State Street
Massachusetts
$299K 33,847 -3,668,593 -99%
Canada Pension Plan Investment Board
29
Canada Pension Plan Investment Board
Ontario, Canada
$260K 29,411 -558,824 -95%
Walleye Capital
30
Walleye Capital
New York
$258K 29,230 +29,230 New
Acadian Asset Management
31
Acadian Asset Management
Massachusetts
$241K 27,366 -633,533 -96%
Morgan Stanley
32
Morgan Stanley
New York
$227K 25,698 -840,705 -97%
UBS Group
33
UBS Group
Switzerland
$227K 25,634 -84,767 -77%
Manulife (Manufacturers Life Insurance)
34
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$216K 24,419 -489,409 -95%
Bank of America
35
Bank of America
North Carolina
$210K 23,758 -70,312 -75%
SPS
36
Susquehanna Portfolio Strategies
Pennsylvania
$192K 21,700 +21,700 New
CGL
37
Clarius Group LLC
Washington
$169K 19,138 -380,030 -95%
Northern Trust
38
Northern Trust
Illinois
$165K 18,644 -1,276,429 -99%
BCM
39
Bridgeway Capital Management
Texas
$159K 18,000 +18,000 New
Invesco
40
Invesco
Georgia
$113K 12,809 -366,071 -97%
BFM
41
Boothbay Fund Management
New York
$108K 12,234 -232,480 -95%
Marshall Wace
42
Marshall Wace
United Kingdom
$93.5K 10,580 +10,580 New
Two Sigma Investments
43
Two Sigma Investments
New York
$88.9K 10,059 -377,621 -97%
Raymond James Financial
44
Raymond James Financial
Florida
$69.8K 7,900 -150,100 -95%
JPMorgan Chase & Co
45
JPMorgan Chase & Co
New York
$29.8K 3,369 -191,282 -98%
Fidelity Investments
46
Fidelity Investments
Massachusetts
$27.2K 3,077 -16,258 -84%
CUAMC
47
China Universal Asset Management Company
China
$26.2K 2,966 -55,637 -95%
TRCT
48
Tower Research Capital (TRC)
New York
$18.6K 2,103 -22,166 -91%
Citigroup
49
Citigroup
New York
$18.2K 2,055 -115,850 -98%
Jones Financial Companies
50
Jones Financial Companies
Missouri
$17.9K 2,000 -38,000 -95%
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