LeonaBio Inc
LONA
42 hedge funds and large institutions have $46.7M invested in LeonaBio Inc in 2025 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 8 increasing their positions, 6 reducing their positions, and 7 closing their positions.
513% more capital invested
Capital invested by funds: $7.62M → $46.7M (+$39.1M)
152.99% more ownership
Funds ownership: 4.35% → 157.34% (+153%)
114% more first-time investments, than exits
New positions opened: 15 | Existing positions closed: 7
33% more repeat investments, than reductions
Existing positions increased: 8 | Existing positions reduced: 6
24% more funds holding
Funds holding: 34 → 42 (+8)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PA
Perceptive Advisors
New York
|
+$6.04M |
| 2 |
ACA
Acorn Capital Advisors
New York
|
+$2.3M |
| 3 |
CC
Commodore Capital
New York
|
+$2.13M |
| 4 |
NMC
NEA Management Company
Timonium,
Maryland
|
+$2.13M |
| 5 |
TCM
TCG Crossover Management
Palo Alto,
California
|
+$2.13M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BCM
BML Capital Management
Zionsville,
Indiana
|
-$1.34M |
| 2 |
Focus Partners Wealth
Boston,
Massachusetts
|
-$558K |
| 3 |
TCM
Tang Capital Management
San Diego,
California
|
-$248K |
| 4 |
Citadel Advisors
Miami,
Florida
|
-$141K |
| 5 |
Two Sigma Advisers
New York
|
-$61.5K |
LONA Hedge Fund Activity: Q4 2025 in Review
42 of the 8,257 institutional investors tracked by Wall St. Rank reported a position in LeonaBio Inc (LONA) for Q4 2025, worth a combined $46.7M — up 513% from $7.62M a quarter earlier.
Buyers outnumbered sellers: 15 funds opened new LONA positions and 7 closed out — a net gain of 8 holders — while 8 added to existing stakes and 6 trimmed.
The largest buyer was Perceptive Advisors, adding an estimated $6.04M. The largest seller was BML Capital Management, exiting entirely with an estimated $1.34M sold.
- 42 institutional investors held LeonaBio Inc (LONA) as of Q4 2025, up from 34 in Q3 2025.
- Funds reported $46.7M of LeonaBio Inc stock for Q4 2025, up 513% quarter-over-quarter.
- 15 funds opened new LeonaBio Inc positions in Q4 2025 and 7 closed out, a net change of +8 holders.
- The largest LeonaBio Inc buyer in Q4 2025 was Perceptive Advisors, an estimated $6.04M added.
- The largest LeonaBio Inc seller in Q4 2025 was BML Capital Management, an estimated $1.34M sold.
Based on aggregated 13F filings for Q4 2025.