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LONA

LeonaBio Inc
LONA

40 hedge funds and large institutions have $66M invested in LeonaBio Inc in 2026 Q1 according to their latest regulatory filings, with 6 funds opening new positions, 11 increasing their positions, 6 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed

83% more repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 6

41% more capital invested

Capital invested by funds: $46.7M → $66M (+$19.3M)

0% more first-time investments, than exits

New positions opened: 6 | Existing positions closed: 6

5% less funds holding

Funds holding: 42 → 40 (-2)

88.2% less ownership

Funds ownership: 157.34% → 69.13% (-88%)

Holders
40
Holders Change
-2
Holders Change %
-4.76%
% of All Funds
0.49%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
6
Increased
11
Reduced
6
Closed
6
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
ACM
ADAR1 Capital Management
Texas
+$2.17M
2
ACA
Acorn Capital Advisors
New York
+$864K
3
Geode Capital Management
Geode Capital Management
Massachusetts
+$321K
4
SFCM
Seven Fleet Capital Management
California
+$239K
5
BlackRock
BlackRock
New York
+$120K

Top Sellers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
-$1.9M
2
Pathstone Holdings
Pathstone Holdings
New Jersey
-$279K
3
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$177K
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$158K
5
Jane Street
Jane Street
New York
-$99.8K
Name Holding Trade Value Shares
Change 		Change in
Stake
PA
1
Perceptive Advisors
New York
$19.1M – – –
ACM
2
ADAR1 Capital Management
Texas
$7.48M +$2.17M +333,780 +85%
ACA
3
Acorn Capital Advisors
New York
$6.52M +$864K +132,800 +26%
CC
4
Commodore Capital
New York
$4.77M – – –
NMC
5
NEA Management Company
Maryland
$4.77M – – –
TCM
6
TCG Crossover Management
California
$4.67M – – –
KCM
7
Kalehua Capital Management
Texas
$4.05M – – –
SSC
8
Spruce Street Capital
New York
$3.84M – – –
Vanguard Capital Management
9
Vanguard Capital Management
Pennsylvania
$2M +$1.27M +194,760 New
SFCM
10
Seven Fleet Capital Management
California
$1.69M +$239K +36,725 +29%
SAM
11
Simplify Asset Management
Nevada
$1.53M – – –
PBM
12
Propel Bio Management
California
$1.5M – – –
Geode Capital Management
13
Geode Capital Management
Massachusetts
$826K +$321K +49,379 +160%
Renaissance Technologies
14
Renaissance Technologies
New York
$660K -$71K -10,925 -15%
BlackRock
15
BlackRock
New York
$576K +$120K +18,408 +49%
Vanguard Fiduciary Trust
16
Vanguard Fiduciary Trust
Pennsylvania
$412K +$260K +40,039 New
Bank of America
17
Bank of America
North Carolina
$335K -$1.78K -274 -0.8%
Millennium Management
18
Millennium Management
New York
$326K -$1.9M -292,767 -90%
LNWTC
19
Laird Norton Wetherby Trust Company
Washington
$224K – – –
State Street
20
State Street
Massachusetts
$168K +$36.4K +5,600 +52%
Northern Trust
21
Northern Trust
Illinois
$148K +$25.6K +3,933 +38%
Two Sigma Investments
22
Two Sigma Investments
New York
$136K +$16.5K +2,530 +24%
Acadian Asset Management
23
Acadian Asset Management
Massachusetts
$105K -$177K -27,252 -73%
Osaic Holdings
24
Osaic Holdings
Arizona
$63.5K -$19.7K -3,030 -33%
Royal Bank of Canada
25
Royal Bank of Canada
Ontario, Canada
$23K +$12.3K +1,891 +566%
1
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LONA Hedge Fund Activity: Q1 2026 in Review

40 of the 8,169 institutional investors tracked by Wall St. Rank reported a position in LeonaBio Inc (LONA) for Q1 2026, worth a combined $66M — up 41% from $46.7M a quarter earlier.

Fund positioning in LONA was balanced in Q1 2026: 6 funds opened new positions, 6 closed out, 11 added to existing stakes and 6 trimmed.

The largest buyer was ADAR1 Capital Management, adding an estimated $2.17M. The largest seller was Millennium Management, cutting an estimated $1.9M.

  • 40 institutional investors held LeonaBio Inc (LONA) as of Q1 2026, down from 42 in Q4 2025.
  • Funds reported $66M of LeonaBio Inc stock for Q1 2026, up 41% quarter-over-quarter.
  • 6 funds opened new LeonaBio Inc positions in Q1 2026 and 6 closed out, a net change of 0 holders.
  • The largest LeonaBio Inc buyer in Q1 2026 was ADAR1 Capital Management, an estimated $2.17M added.
  • The largest LeonaBio Inc seller in Q1 2026 was Millennium Management, an estimated $1.9M sold.

Based on aggregated 13F filings for Q1 2026.