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Kymera Therapeutics

210 hedge funds and large institutions have $4.58B invested in Kymera Therapeutics in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 81 increasing their positions, 54 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

167% more call options, than puts

Call options by funds: $8.81M | Put options by funds: $3.3M

50% more repeat investments, than reductions

Existing positions increased: 81 | Existing positions reduced: 54

33% more capital invested

Capital invested by funds: $3.44B → $4.58B (+$1.14B)

5% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 38

0% more funds holding

Funds holding: 210210 (0)

8% less funds holding in top 10

Funds holding in top 10: 1312 (-1)

7.91% less ownership

Funds ownership: 121.01%113.1% (-7.9%)

Holders
210
Holders Change
Holders Change %
0%
% of All Funds
2.76%
Holding in Top 10
12
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.69%
% of All Funds
0.16%
New
40
Increased
81
Reduced
54
Closed
38
Calls
$8.81M
Puts
$3.3M
Net Calls
+$5.51M
Net Calls Change
-$1.42M
Name Holding Trade Value Shares
Change
Change in
Stake
PS
201
Principal Securities
Iowa
$283
WANY
202
Wealthspire Advisors (New York)
New York
$283 +$226 +5 New
DPW
203
DiNuzzo Private Wealth
Pennsylvania
$83 +$90 +2 New
RWM
204
Rialto Wealth Management
New York
$57
SIC
205
SJS Investment Consulting
Ohio
$57
HIA
206
HFM Investment Advisors
New Jersey
$57 +$45 +1 New
JWA
207
JFS Wealth Advisors
Pennsylvania
$57 +$45 +1 New
RG
208
Redmile Group
California
-$35.1M -803,289 Closed
SCM
209
Suvretta Capital Management
New York
-$12M -275,000 Closed
Voloridge Investment Management
210
Voloridge Investment Management
Florida
-$7.08M -162,315 Closed
ECM
211
ExodusPoint Capital Management
New York
-$4.41M -100,997 Closed
Axa
212
Axa
France
-$3.97M -90,971 Closed
MIM
213
Monashee Investment Management
Massachusetts
-$3.71M -85,000 Closed
WAM
214
Weiss Asset Management
Massachusetts
-$2.22M -50,787 Closed
MS
215
Maven Securities
Jersey
-$2.18M -50,000 Closed
Norges Bank
216
Norges Bank
Norway
-$1.81M -41,370 Closed
Skandinaviska Enskilda Banken (SEB)
217
Skandinaviska Enskilda Banken (SEB)
Sweden
-$1.66M -38,141 Closed
RA
218
Royce & Associates
New York
-$1.47M -33,797 Closed
HF
219
HRT Financial
New York
-$1.26M -28,906 Closed
CM
220
Caption Management
Oklahoma
-$974K -21,600 Closed
ACM
221
ADAR1 Capital Management
Texas
-$583K -13,366 Closed
PHK
222
Point72 Hong Kong
Hong Kong
-$504K -11,546 Closed
CHAM
223
Clear Harbor Asset Management
Connecticut
-$489K -11,194 Closed
BHCM
224
Brevan Howard Capital Management
Jersey
-$485K -11,107 Closed
AG
225
Algert Global
California
-$473K -10,850 Closed

KYMR Hedge Fund Activity: Q3 2025 in Review

210 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q3 2025, worth a combined $4.58B — up 33% from $3.44B a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new KYMR positions and 38 closed out — a net gain of 2 holders — while 81 added to existing stakes and 54 trimmed.

The largest buyer was Holocene Advisors, opening a new position worth an estimated $37.9M. The largest seller was T. Rowe Price Associates, cutting an estimated $79.5M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q3 2025, unchanged from Q2 2025.
  • Funds reported $4.58B of Kymera Therapeutics stock for Q3 2025, up 33% quarter-over-quarter.
  • 40 funds opened new Kymera Therapeutics positions in Q3 2025 and 38 closed out, a net change of +2 holders.
  • The largest Kymera Therapeutics buyer in Q3 2025 was Holocene Advisors, an estimated $37.9M added.
  • The largest Kymera Therapeutics seller in Q3 2025 was T. Rowe Price Associates, an estimated $79.5M sold.

Based on aggregated 13F filings for Q3 2025.