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Kymera Therapeutics

254 hedge funds and large institutions have $6.99B invested in Kymera Therapeutics in 2025 Q4 according to their latest regulatory filings, with 68 funds opening new positions, 97 increasing their positions, 64 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

325% more first-time investments, than exits

New positions opened: 68 | Existing positions closed: 16

53% more capital invested

Capital invested by funds: $4.58B → $6.99B (+$2.41B)

52% more repeat investments, than reductions

Existing positions increased: 97 | Existing positions reduced: 64

21% more funds holding

Funds holding: 210254 (+44)

11.78% more ownership

Funds ownership: 113.1%124.88% (+12%)

8% more funds holding in top 10

Funds holding in top 10: 1213 (+1)

41% less call options, than puts

Call options by funds: $9.18M | Put options by funds: $15.6M

Holders
254
Holders Change
+44
Holders Change %
+20.95%
% of All Funds
3.09%
Holding in Top 10
13
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+8.33%
% of All Funds
0.16%
New
68
Increased
97
Reduced
64
Closed
16
Calls
$9.18M
Puts
$15.6M
Net Calls
-$6.45M
Net Calls Change
-$12M
Name Holding Trade Value Shares
Change
Change in
Stake
VPIM
176
Vanguard Personalized Indexing Management
California
$284K +$246K +3,646 New
Mirae Asset Global Investments
177
Mirae Asset Global Investments
South Korea
$272K +$49.4K +732 +26%
Mackenzie Financial
178
Mackenzie Financial
Ontario, Canada
$270K +$234K +3,464 New
Ameriprise
179
Ameriprise
Minnesota
$267K -$1.39M -20,632 -86%
Prudential Financial
180
Prudential Financial
New Jersey
$265K -$212K -3,140 -48%
Cetera Investment Advisers
181
Cetera Investment Advisers
Illinois
$261K +$226K +3,350 New
Principal Financial Group
182
Principal Financial Group
Iowa
$259K -$35.5K -525 -14%
Belvedere Trading
183
Belvedere Trading
Illinois
$255K +$222K +3,282 New
PAG
184
Private Advisor Group
New Jersey
$252K +$219K +3,239 New
VIA
185
Virtus Investment Advisers
Connecticut
$231K +$37.8K +560 +23%
CIBC Asset Management
186
CIBC Asset Management
Ontario, Canada
$229K +$198K +2,939 New
MFG
187
Mosaic Financial Group
Illinois
$225K +$195K +2,890 New
BCI
188
Brinker Capital Investments
Pennsylvania
$223K +$194K +2,868 New
American Century Companies
189
American Century Companies
Missouri
$219K +$190K +2,819 New
DWM
190
Drive Wealth Management
Utah
$218K +$189K +2,797 New
ACM
191
Aquatic Capital Management
Illinois
$209K -$855K -12,663 -82%
PCP
192
Perbak Capital Partners
United Kingdom
$205K -$329K -4,866 -65%
CIAM
193
Caitong International Asset Management
Hong Kong
$198K +$172K +2,542 New
Royal Bank of Canada
194
Royal Bank of Canada
Ontario, Canada
$176K -$15.8M -234,711 -99%
US Bancorp
195
US Bancorp
Minnesota
$174K +$25.3K +375 +20%
AB
196
Amalgamated Bank
New York
$138K +$9.86K +146 +9%
KBC Group
197
KBC Group
Belgium
$134K
Los Angeles Capital Management
198
Los Angeles Capital Management
California
$121K +$133K +1,968 New
GFM
199
GF Fund Management
China
$110K -$8.44K -125 -8%
Osaic Holdings
200
Osaic Holdings
Arizona
$107K +$4.79K +71 +5%