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Kymera Therapeutics

210 hedge funds and large institutions have $3.44B invested in Kymera Therapeutics in 2025 Q2 according to their latest regulatory filings, with 64 funds opening new positions, 69 increasing their positions, 52 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

219% more call options, than puts

Call options by funds: $10.1M | Put options by funds: $3.16M

146% more first-time investments, than exits

New positions opened: 64 | Existing positions closed: 26

72% more capital invested

Capital invested by funds: $2B → $3.44B (+$1.44B)

44% more funds holding in top 10

Funds holding in top 10: 913 (+4)

33% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 52

21% more funds holding

Funds holding: 173210 (+37)

8.82% more ownership

Funds ownership: 112.19%121.01% (+8.8%)

Holders
210
Holders Change
+37
Holders Change %
+21.39%
% of All Funds
2.76%
Holding in Top 10
13
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+44.44%
% of All Funds
0.17%
New
64
Increased
69
Reduced
52
Closed
26
Calls
$10.1M
Puts
$3.16M
Net Calls
+$6.93M
Net Calls Change
+$5.69M
Name Holding Trade Value Shares
Change
Change in
Stake
SPS
151
Susquehanna Portfolio Strategies
Pennsylvania
$246K +$194K +5,644 New
Pictet Asset Management
152
Pictet Asset Management
Switzerland
$243K +$191K +5,558 New
TRCT
153
Tower Research Capital (TRC)
New York
$237K +$98.4K +2,858 +111%
PD
154
Point72 (DIFC)
United Arab Emirates
$231K +$182K +5,289 New
A
155
AlphaQuest
New York
$222K +$175K +5,090 New
Hudson Bay Capital Management
156
Hudson Bay Capital Management
Connecticut
$218K +$172K +5,000 New
BNP Paribas Financial Markets
157
BNP Paribas Financial Markets
France
$217K +$53.9K +1,565 +46%
GIM
158
Glenmede Investment Management
Pennsylvania
$217K +$172K +4,981 New
AAM
159
Advisors Asset Management
Colorado
$217K +$103 +3 +0.1%
AIP
160
Ameritas Investment Partners
Nebraska
$214K
KCM
161
Kennedy Capital Management
Missouri
$211K +$167K +4,836 New
Public Employees Retirement Association of Colorado
162
Public Employees Retirement Association of Colorado
Colorado
$204K
OAM
163
Oxford Asset Management
United Kingdom
$201K +$158K +4,598 New
BIG
164
Brooklyn Investment Group
New York
$190K +$149K +4,338 +72,300%
SAM
165
Shell Asset Management
Netherlands
$167K -$3.75K -109 -3%
Lazard Asset Management
166
Lazard Asset Management
New York
$116K +$91.7K +2,664 New
N
167
Natixis
France
$113K -$347K -10,079 -80%
Mirae Asset Global Investments
168
Mirae Asset Global Investments
South Korea
$110K +$11.8K +343 +16%
VIA
169
Virtus Investment Advisers
Connecticut
$86.8K -$65.5K -1,903 -49%
KBC Group
170
KBC Group
Belgium
$75K -$26.3K -763 -31%
US Bancorp
171
US Bancorp
Minnesota
$74.1K +$19.8K +575 +51%
Raymond James Financial
172
Raymond James Financial
Florida
$72.6K +$57.3K +1,664 New
GFM
173
GF Fund Management
China
$72.4K
AB
174
Amalgamated Bank
New York
$71K
Osaic Holdings
175
Osaic Holdings
Arizona
$47.5K +$37.3K +1,083 +18,050%

KYMR Hedge Fund Activity: Q2 2025 in Review

210 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q2 2025, worth a combined $3.44B — up 72% from $2B a quarter earlier.

Buyers outnumbered sellers: 64 funds opened new KYMR positions and 26 closed out — a net gain of 38 holders — while 69 added to existing stakes and 52 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $35.2M. The largest seller was Janus Henderson Group, cutting an estimated $25.9M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q2 2025, up from 173 in Q1 2025.
  • Funds reported $3.44B of Kymera Therapeutics stock for Q2 2025, up 72% quarter-over-quarter.
  • 64 funds opened new Kymera Therapeutics positions in Q2 2025 and 26 closed out, a net change of +38 holders.
  • The largest Kymera Therapeutics buyer in Q2 2025 was Fidelity Investments, an estimated $35.2M added.
  • The largest Kymera Therapeutics seller in Q2 2025 was Janus Henderson Group, an estimated $25.9M sold.

Based on aggregated 13F filings for Q2 2025.