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Kymera Therapeutics

210 hedge funds and large institutions have $3.44B invested in Kymera Therapeutics in 2025 Q2 according to their latest regulatory filings, with 64 funds opening new positions, 69 increasing their positions, 52 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

219% more call options, than puts

Call options by funds: $10.1M | Put options by funds: $3.16M

146% more first-time investments, than exits

New positions opened: 64 | Existing positions closed: 26

72% more capital invested

Capital invested by funds: $2B → $3.44B (+$1.44B)

44% more funds holding in top 10

Funds holding in top 10: 913 (+4)

33% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 52

21% more funds holding

Funds holding: 173210 (+37)

8.82% more ownership

Funds ownership: 112.19%121.01% (+8.8%)

Holders
210
Holders Change
+37
Holders Change %
+21.39%
% of All Funds
2.76%
Holding in Top 10
13
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+44.44%
% of All Funds
0.17%
New
64
Increased
69
Reduced
52
Closed
26
Calls
$10.1M
Puts
$3.16M
Net Calls
+$6.93M
Net Calls Change
+$5.69M
Name Holding Trade Value Shares
Change
Change in
Stake
CHAM
126
Clear Harbor Asset Management
Connecticut
$489K +$28.9K +838 +8%
BHCM
127
Brevan Howard Capital Management
Jersey
$485K +$382K +11,107 New
AG
128
Algert Global
California
$473K +$374K +10,850 New
Teacher Retirement System of Texas
129
Teacher Retirement System of Texas
Texas
$458K +$1.58K +46 +0.4%
Canada Life
130
Canada Life
Manitoba, Canada
$458K
PFSRSONJ
131
Police & Firemen's Retirement System of New Jersey
New Jersey
$454K
VF
132
Virtu Financial
New York
$452K +$357K +10,362 New
GCM
133
Ghisallo Capital Management
Massachusetts
$436K +$344K +10,000 New
Cambridge Investment Research Advisors
134
Cambridge Investment Research Advisors
Iowa
$394K +$379 +11 +0.1%
PA
135
Profund Advisors
Maryland
$385K -$128K -3,718 -30%
VA
136
Vident Advisory
Georgia
$376K +$296K +8,606 New
Verition Fund Management
137
Verition Fund Management
Connecticut
$370K -$737K -21,406 -72%
AQR Capital Management
138
AQR Capital Management
Connecticut
$353K +$278K +8,083 New
KK
139
KLP Kapitalforvaltning
Norway
$336K
KMWM
140
Keudell/Morrison Wealth Management
Oregon
$334K +$264K +7,660 New
M1FG
141
Mach-1 Financial Group
Arkansas
$331K +$261K +7,594 New
HSBC Holdings
142
HSBC Holdings
United Kingdom
$318K -$391K -11,353 -61%
PCP
143
Proficio Capital Partners
Massachusetts
$305K +$241K +7,000 New
DC
144
Diametric Capital
Massachusetts
$288K +$227K +6,600 New
I
145
InceptionR
California
$282K +$223K +6,468 New
SEI Investments
146
SEI Investments
Pennsylvania
$265K +$209K +6,075 New
FCM
147
Fieldview Capital Management
Michigan
$259K +$204K +5,929 New
PAS
148
Point72 Asia (Singapore)
Singapore
$257K +$203K +5,882 New
CWM
149
CIBC World Markets
New York
$252K -$160K -4,651 -45%
ACM
150
Aster Capital Management
United Arab Emirates
$247K +$136K +3,945 +230%

KYMR Hedge Fund Activity: Q2 2025 in Review

210 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q2 2025, worth a combined $3.44B — up 72% from $2B a quarter earlier.

Buyers outnumbered sellers: 64 funds opened new KYMR positions and 26 closed out — a net gain of 38 holders — while 69 added to existing stakes and 52 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $35.2M. The largest seller was Janus Henderson Group, cutting an estimated $25.9M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q2 2025, up from 173 in Q1 2025.
  • Funds reported $3.44B of Kymera Therapeutics stock for Q2 2025, up 72% quarter-over-quarter.
  • 64 funds opened new Kymera Therapeutics positions in Q2 2025 and 26 closed out, a net change of +38 holders.
  • The largest Kymera Therapeutics buyer in Q2 2025 was Fidelity Investments, an estimated $35.2M added.
  • The largest Kymera Therapeutics seller in Q2 2025 was Janus Henderson Group, an estimated $25.9M sold.

Based on aggregated 13F filings for Q2 2025.