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Kymera Therapeutics

210 hedge funds and large institutions have $4.58B invested in Kymera Therapeutics in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 81 increasing their positions, 54 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

167% more call options, than puts

Call options by funds: $8.81M | Put options by funds: $3.3M

50% more repeat investments, than reductions

Existing positions increased: 81 | Existing positions reduced: 54

33% more capital invested

Capital invested by funds: $3.44B → $4.58B (+$1.14B)

5% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 38

0% more funds holding

Funds holding: 210210 (0)

8% less funds holding in top 10

Funds holding in top 10: 1312 (-1)

7.91% less ownership

Funds ownership: 121.01%113.1% (-7.9%)

Holders
210
Holders Change
Holders Change %
0%
% of All Funds
2.76%
Holding in Top 10
12
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.69%
% of All Funds
0.16%
New
40
Increased
81
Reduced
54
Closed
38
Calls
$8.81M
Puts
$3.3M
Net Calls
+$5.51M
Net Calls Change
-$1.42M
Name Holding Trade Value Shares
Change
Change in
Stake
State of Wisconsin Investment Board
101
State of Wisconsin Investment Board
Wisconsin
$1.57M -$226K -5,000 -15%
Mirae Asset Global ETFs Holdings
102
Mirae Asset Global ETFs Holdings
Hong Kong
$1.53M -$31.3K -693 -3%
New York State Common Retirement Fund
103
New York State Common Retirement Fund
New York
$1.38M +$444K +9,847 +68%
Ameriprise
104
Ameriprise
Minnesota
$1.36M +$204K +4,525 +23%
Hudson Bay Capital Management
105
Hudson Bay Capital Management
Connecticut
$1.31M +$818K +18,134 +363%
CUAMC
106
China Universal Asset Management Company
China
$1.28M -$24.7K -547 -2%
Handelsbanken Fonder
107
Handelsbanken Fonder
Sweden
$1.23M +$235K +5,200 +32%
NICM
108
Neo Ivy Capital Management
New York
$1.11M -$37.8K -839 -4%
Russell Investments Group
109
Russell Investments Group
United Kingdom
$1.07M -$348K -7,709 -29%
KOCAA
110
Knights of Columbus Asset Advisors
Connecticut
$1.07M +$852K +18,891 New
Janus Henderson Group
111
Janus Henderson Group
United Kingdom
$1.04M -$45.1K -1,000 -5%
TRSOTSOK
112
Teachers Retirement System of the State of Kentucky
Kentucky
$1.01M
HS
113
HighVista Strategies
Massachusetts
$890K +$709K +15,728 New
DekaBank Deutsche Girozentrale
114
DekaBank Deutsche Girozentrale
Germany
$869K
ACM
115
Aquatic Capital Management
Illinois
$869K -$74.8K -1,658 -10%
SEI Investments
116
SEI Investments
Pennsylvania
$863K +$414K +9,171 +151%
PA
117
Profund Advisors
Maryland
$850K +$279K +6,182 +70%
Zurich Cantonal Bank
118
Zurich Cantonal Bank
Switzerland
$840K +$71.4K +1,583 +12%
IIM
119
INTECH Investment Management
Florida
$833K -$373K -8,279 -36%
PFSRSONJ
120
Police & Firemen's Retirement System of New Jersey
New Jersey
$789K +$159K +3,529 +34%
SPS
121
Susquehanna Portfolio Strategies
Pennsylvania
$779K +$366K +8,124 +144%
ASRS
122
Arizona State Retirement System
Arizona
$704K +$48.8K +1,081 +10%
State Board of Administration of Florida Retirement System
123
State Board of Administration of Florida Retirement System
Florida
$693K
AIM
124
Aigen Investment Management
New York
$672K +$536K +11,877 New
ProShare Advisors
125
ProShare Advisors
Maryland
$632K -$38.8K -860 -7%

KYMR Hedge Fund Activity: Q3 2025 in Review

210 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q3 2025, worth a combined $4.58B — up 33% from $3.44B a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new KYMR positions and 38 closed out — a net gain of 2 holders — while 81 added to existing stakes and 54 trimmed.

The largest buyer was Holocene Advisors, opening a new position worth an estimated $37.9M. The largest seller was T. Rowe Price Associates, cutting an estimated $79.5M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q3 2025, unchanged from Q2 2025.
  • Funds reported $4.58B of Kymera Therapeutics stock for Q3 2025, up 33% quarter-over-quarter.
  • 40 funds opened new Kymera Therapeutics positions in Q3 2025 and 38 closed out, a net change of +2 holders.
  • The largest Kymera Therapeutics buyer in Q3 2025 was Holocene Advisors, an estimated $37.9M added.
  • The largest Kymera Therapeutics seller in Q3 2025 was T. Rowe Price Associates, an estimated $79.5M sold.

Based on aggregated 13F filings for Q3 2025.