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Kymera Therapeutics

210 hedge funds and large institutions have $3.44B invested in Kymera Therapeutics in 2025 Q2 according to their latest regulatory filings, with 64 funds opening new positions, 69 increasing their positions, 52 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

219% more call options, than puts

Call options by funds: $10.1M | Put options by funds: $3.16M

146% more first-time investments, than exits

New positions opened: 64 | Existing positions closed: 26

72% more capital invested

Capital invested by funds: $2B → $3.44B (+$1.44B)

44% more funds holding in top 10

Funds holding in top 10: 913 (+4)

33% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 52

21% more funds holding

Funds holding: 173210 (+37)

8.82% more ownership

Funds ownership: 112.19%121.01% (+8.8%)

Holders
210
Holders Change
+37
Holders Change %
+21.39%
% of All Funds
2.76%
Holding in Top 10
13
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+44.44%
% of All Funds
0.17%
New
64
Increased
69
Reduced
52
Closed
26
Calls
$10.1M
Puts
$3.16M
Net Calls
+$6.93M
Net Calls Change
+$5.69M
Name Holding Trade Value Shares
Change
Change in
Stake
Citigroup
101
Citigroup
New York
$1.25M -$1.8M -52,391 -65%
MIM
102
MetLife Investment Management
New Jersey
$1.21M
Mirae Asset Global ETFs Holdings
103
Mirae Asset Global ETFs Holdings
Hong Kong
$1.21M -$110K -3,182 -10%
EAM
104
Erste Asset Management
Austria
$1.19M
Russell Investments Group
105
Russell Investments Group
United Kingdom
$1.17M -$1.92M -55,807 -68%
DFCM
106
Dark Forest Capital Management
Puerto Rico
$1.13M -$971K -28,204 -52%
Wells Fargo
107
Wells Fargo
California
$1.12M +$108K +3,138 +14%
CUAMC
108
China Universal Asset Management Company
China
$1.01M +$346K +10,052 +77%
IIM
109
INTECH Investment Management
Florida
$1M -$338K -9,802 -30%
SG Americas Securities
110
SG Americas Securities
New York
$963K +$760K +22,065 New
CM
111
Caption Management
Oklahoma
$943K +$744K +21,600 New
NICM
112
Neo Ivy Capital Management
New York
$895K +$209K +6,079 +42%
DekaBank Deutsche Girozentrale
113
DekaBank Deutsche Girozentrale
Germany
$876K
Ameriprise
114
Ameriprise
Minnesota
$852K +$143K +4,159 +27%
Janus Henderson Group
115
Janus Henderson Group
United Kingdom
$842K -$25.9M -751,274 -97%
TRSOTSOK
116
Teachers Retirement System of the State of Kentucky
Kentucky
$781K
ACM
117
Aquatic Capital Management
Illinois
$742K +$586K +17,011 New
Handelsbanken Fonder
118
Handelsbanken Fonder
Sweden
$720K
New York State Common Retirement Fund
119
New York State Common Retirement Fund
New York
$635K
ACM
120
ADAR1 Capital Management
Texas
$583K +$116K +3,366 +34%
Zurich Cantonal Bank
121
Zurich Cantonal Bank
Switzerland
$579K +$65.8K +1,911 +17%
State Board of Administration of Florida Retirement System
122
State Board of Administration of Florida Retirement System
Florida
$534K
ProShare Advisors
123
ProShare Advisors
Maryland
$525K -$36.7K -1,067 -8%
PHK
124
Point72 Hong Kong
Hong Kong
$504K +$398K +11,546 New
ASRS
125
Arizona State Retirement System
Arizona
$495K +$7.13K +207 +2%

KYMR Hedge Fund Activity: Q2 2025 in Review

210 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q2 2025, worth a combined $3.44B — up 72% from $2B a quarter earlier.

Buyers outnumbered sellers: 64 funds opened new KYMR positions and 26 closed out — a net gain of 38 holders — while 69 added to existing stakes and 52 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $35.2M. The largest seller was Janus Henderson Group, cutting an estimated $25.9M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q2 2025, up from 173 in Q1 2025.
  • Funds reported $3.44B of Kymera Therapeutics stock for Q2 2025, up 72% quarter-over-quarter.
  • 64 funds opened new Kymera Therapeutics positions in Q2 2025 and 26 closed out, a net change of +38 holders.
  • The largest Kymera Therapeutics buyer in Q2 2025 was Fidelity Investments, an estimated $35.2M added.
  • The largest Kymera Therapeutics seller in Q2 2025 was Janus Henderson Group, an estimated $25.9M sold.

Based on aggregated 13F filings for Q2 2025.