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Kymera Therapeutics

210 hedge funds and large institutions have $3.44B invested in Kymera Therapeutics in 2025 Q2 according to their latest regulatory filings, with 64 funds opening new positions, 69 increasing their positions, 52 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

219% more call options, than puts

Call options by funds: $10.1M | Put options by funds: $3.16M

146% more first-time investments, than exits

New positions opened: 64 | Existing positions closed: 26

72% more capital invested

Capital invested by funds: $2B → $3.44B (+$1.44B)

44% more funds holding in top 10

Funds holding in top 10: 913 (+4)

33% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 52

21% more funds holding

Funds holding: 173210 (+37)

8.82% more ownership

Funds ownership: 112.19%121.01% (+8.8%)

Holders
210
Holders Change
+37
Holders Change %
+21.39%
% of All Funds
2.76%
Holding in Top 10
13
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+44.44%
% of All Funds
0.17%
New
64
Increased
69
Reduced
52
Closed
26
Calls
$10.1M
Puts
$3.16M
Net Calls
+$6.93M
Net Calls Change
+$5.69M
Name Holding Trade Value Shares
Change
Change in
Stake
Millennium Management
76
Millennium Management
New York
$2.47M -$15.6M -453,944 -89%
Deutsche Bank
77
Deutsche Bank
Germany
$2.22M -$106K -3,092 -6%
WAM
78
Weiss Asset Management
Massachusetts
$2.22M +$1.75M +50,787 New
TI
79
Trexquant Investment
Connecticut
$2.21M +$1.74M +50,663 New
Alyeska Investment Group
80
Alyeska Investment Group
Illinois
$2.18M +$1.72M +50,000 New
MS
81
Maven Securities
Jersey
$2.18M +$1.72M +50,000 New
Comerica Bank
82
Comerica Bank
Texas
$2.14M +$955K +27,739 +130%
Invesco
83
Invesco
Georgia
$2.09M +$200K +5,809 +14%
AllianceBernstein
84
AllianceBernstein
Tennessee
$2.05M +$70.6K +2,050 +5%
Legal & General Group
85
Legal & General Group
United Kingdom
$1.81M +$51.2K +1,486 +4%
Norges Bank
86
Norges Bank
Norway
$1.81M -$287K -8,327 -17%
Rafferty Asset Management
87
Rafferty Asset Management
New York
$1.75M -$649K -18,844 -32%
JG
88
Jain Global
New York
$1.69M +$1.33M +38,705 New
Skandinaviska Enskilda Banken (SEB)
89
Skandinaviska Enskilda Banken (SEB)
Sweden
$1.66M
California State Teachers Retirement System (CalSTRS)
90
California State Teachers Retirement System (CalSTRS)
California
$1.58M -$17.9K -521 -1%
MAP
91
Moody Aldrich Partners
Massachusetts
$1.52M +$1.2M +34,797 New
RA
92
Royce & Associates
New York
$1.47M +$1.16M +33,797 New
Franklin Resources
93
Franklin Resources
California
$1.47M +$28.3K +822 +3%
HCA
94
Harbor Capital Advisors
Illinois
$1.46M +$89.3K +2,594 +8%
Squarepoint
95
Squarepoint
New York
$1.45M -$546K -15,865 -32%
State of Wisconsin Investment Board
96
State of Wisconsin Investment Board
Wisconsin
$1.43M -$842K -24,448 -43%
NFGH
97
Nan Fung Group Holdings
Hong Kong
$1.35M
VOYA Investment Management
98
VOYA Investment Management
Georgia
$1.3M -$304K -8,838 -23%
Victory Capital Management
99
Victory Capital Management
Texas
$1.29M +$571K +16,593 +127%
HF
100
HRT Financial
New York
$1.26M +$995K +28,906 New

KYMR Hedge Fund Activity: Q2 2025 in Review

210 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q2 2025, worth a combined $3.44B — up 72% from $2B a quarter earlier.

Buyers outnumbered sellers: 64 funds opened new KYMR positions and 26 closed out — a net gain of 38 holders — while 69 added to existing stakes and 52 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $35.2M. The largest seller was Janus Henderson Group, cutting an estimated $25.9M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q2 2025, up from 173 in Q1 2025.
  • Funds reported $3.44B of Kymera Therapeutics stock for Q2 2025, up 72% quarter-over-quarter.
  • 64 funds opened new Kymera Therapeutics positions in Q2 2025 and 26 closed out, a net change of +38 holders.
  • The largest Kymera Therapeutics buyer in Q2 2025 was Fidelity Investments, an estimated $35.2M added.
  • The largest Kymera Therapeutics seller in Q2 2025 was Janus Henderson Group, an estimated $25.9M sold.

Based on aggregated 13F filings for Q2 2025.