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Kymera Therapeutics

210 hedge funds and large institutions have $4.58B invested in Kymera Therapeutics in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 81 increasing their positions, 54 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

167% more call options, than puts

Call options by funds: $8.81M | Put options by funds: $3.3M

50% more repeat investments, than reductions

Existing positions increased: 81 | Existing positions reduced: 54

33% more capital invested

Capital invested by funds: $3.44B → $4.58B (+$1.14B)

5% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 38

0% more funds holding

Funds holding: 210210 (0)

8% less funds holding in top 10

Funds holding in top 10: 1312 (-1)

7.91% less ownership

Funds ownership: 121.01%113.1% (-7.9%)

Holders
210
Holders Change
Holders Change %
0%
% of All Funds
2.76%
Holding in Top 10
12
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.69%
% of All Funds
0.16%
New
40
Increased
81
Reduced
54
Closed
38
Calls
$8.81M
Puts
$3.3M
Net Calls
+$5.51M
Net Calls Change
-$1.42M
Name Holding Trade Value Shares
Change
Change in
Stake
Royal Bank of Canada
51
Royal Bank of Canada
Ontario, Canada
$13.4M +$3.64M +80,721 +52%
TD Asset Management
52
TD Asset Management
Ontario, Canada
$11.8M -$1.16M -25,722 -11%
JP Morgan Chase
53
JP Morgan Chase
New York
$10.9M -$678K -15,023 -7%
CS
54
Candriam SCA
Luxembourg
$10.8M +$1.69M +37,536 +24%
Bank of America
55
Bank of America
North Carolina
$10.5M +$2.31M +51,315 +38%
Point72 Asset Management
56
Point72 Asset Management
Connecticut
$9.84M -$477K -10,578 -6%
PA
57
Perceptive Advisors
New York
$9.61M -$1.82M -40,310 -19%
Barclays
58
Barclays
United Kingdom
$8.78M +$540K +11,963 +8%
Bank of New York Mellon
59
Bank of New York Mellon
New York
$8.63M +$980K +21,738 +17%
FCMV
60
Foresite Capital Management VI
California
$8.28M
Manulife (Manufacturers Life Insurance)
61
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$7.16M -$1.16M -25,675 -17%
YCM
62
Yiheng Capital Management
California
$6.94M
Universal-Beteiligungs- und Servicegesellschaft
63
Universal-Beteiligungs- und Servicegesellschaft
Germany
$6.1M +$12K +265 +0.2%
N
64
Nuveen
North Carolina
$6.04M +$282K +6,258 +6%
Millennium Management
65
Millennium Management
New York
$5.37M +$1.73M +38,425 +68%
PSC
66
Patient Square Capital
California
$5.24M -$2.14M -47,408 -34%
Ensign Peak Advisors
67
Ensign Peak Advisors
Utah
$5.2M
Swiss National Bank
68
Swiss National Bank
Switzerland
$4.62M +$325K +7,200 +10%
ACM
69
Atika Capital Management
New York
$4.6M -$2.95M -65,300 -45%
AIM
70
AXA Investment Managers
France
$4.56M +$3.63M +80,534 New
Invesco
71
Invesco
Georgia
$4.52M +$1.44M +31,923 +67%
BGM
72
Burkehill Global Management
New York
$4.25M
First Trust Advisors
73
First Trust Advisors
Illinois
$4.24M +$3.38M +74,852 New
RhumbLine Advisers
74
RhumbLine Advisers
Massachusetts
$4.2M +$140K +3,115 +4%
TI
75
Trexquant Investment
Connecticut
$4.13M +$1M +22,261 +44%

KYMR Hedge Fund Activity: Q3 2025 in Review

210 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q3 2025, worth a combined $4.58B — up 33% from $3.44B a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new KYMR positions and 38 closed out — a net gain of 2 holders — while 81 added to existing stakes and 54 trimmed.

The largest buyer was Holocene Advisors, opening a new position worth an estimated $37.9M. The largest seller was T. Rowe Price Associates, cutting an estimated $79.5M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q3 2025, unchanged from Q2 2025.
  • Funds reported $4.58B of Kymera Therapeutics stock for Q3 2025, up 33% quarter-over-quarter.
  • 40 funds opened new Kymera Therapeutics positions in Q3 2025 and 38 closed out, a net change of +2 holders.
  • The largest Kymera Therapeutics buyer in Q3 2025 was Holocene Advisors, an estimated $37.9M added.
  • The largest Kymera Therapeutics seller in Q3 2025 was T. Rowe Price Associates, an estimated $79.5M sold.

Based on aggregated 13F filings for Q3 2025.