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Kymera Therapeutics

210 hedge funds and large institutions have $3.44B invested in Kymera Therapeutics in 2025 Q2 according to their latest regulatory filings, with 64 funds opening new positions, 69 increasing their positions, 52 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

219% more call options, than puts

Call options by funds: $10.1M | Put options by funds: $3.16M

146% more first-time investments, than exits

New positions opened: 64 | Existing positions closed: 26

72% more capital invested

Capital invested by funds: $2B → $3.44B (+$1.44B)

44% more funds holding in top 10

Funds holding in top 10: 913 (+4)

33% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 52

21% more funds holding

Funds holding: 173210 (+37)

8.82% more ownership

Funds ownership: 112.19%121.01% (+8.8%)

Holders
210
Holders Change
+37
Holders Change %
+21.39%
% of All Funds
2.76%
Holding in Top 10
13
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+44.44%
% of All Funds
0.17%
New
64
Increased
69
Reduced
52
Closed
26
Calls
$10.1M
Puts
$3.16M
Net Calls
+$6.93M
Net Calls Change
+$5.69M
Name Holding Trade Value Shares
Change
Change in
Stake
CS
51
Candriam SCA
Luxembourg
$6.73M +$5.31M +154,103 New
Manulife (Manufacturers Life Insurance)
52
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$6.64M +$330K +9,578 +7%
ACM
53
Atika Capital Management
New York
$6.4M +$5.05M +146,600 New
FCMV
54
Foresite Capital Management VI
California
$6.39M
Barclays
55
Barclays
United Kingdom
$6.25M +$2M +57,969 +68%
PSC
56
Patient Square Capital
California
$6.11M -$75.8K -2,201 -2%
Bank of America
57
Bank of America
North Carolina
$5.89M +$1.31M +38,134 +39%
Bank of New York Mellon
58
Bank of New York Mellon
New York
$5.7M +$132K +3,837 +3%
YCM
59
Yiheng Capital Management
California
$5.35M
CSS
60
Cubist Systematic Strategies
Connecticut
$5.18M +$4.09M +118,752 New
Schroder Investment Management Group
61
Schroder Investment Management Group
United Kingdom
$4.81M -$1.66M -48,125 -30%
Universal-Beteiligungs- und Servicegesellschaft
62
Universal-Beteiligungs- und Servicegesellschaft
Germany
$4.69M +$771K +22,392 +26%
CC
63
Checkpoint Capital
California
$4.67M -$1.02M -29,614 -22%
ECM
64
ExodusPoint Capital Management
New York
$4.41M +$2.46M +71,496 +242%
N
65
Nuveen
North Carolina
$4.38M -$1.47M -42,791 -30%
Ensign Peak Advisors
66
Ensign Peak Advisors
Utah
$4.01M +$3.16M +91,897 New
Axa
67
Axa
France
$3.97M -$621K -18,023 -17%
T. Rowe Price Investment Management
68
T. Rowe Price Investment Management
Maryland
$3.96M +$3.12M +90,628 New
MIM
69
Monashee Investment Management
Massachusetts
$3.71M +$2.93M +85,000 New
BGM
70
Burkehill Global Management
New York
$3.27M +$2.58M +75,000 New
Swiss National Bank
71
Swiss National Bank
Switzerland
$3.25M -$31K -900 -1%
RhumbLine Advisers
72
RhumbLine Advisers
Massachusetts
$3.1M +$38.9K +1,130 +2%
Prudential Financial
73
Prudential Financial
New Jersey
$2.8M -$1.08M -31,260 -33%
SSA
74
Schonfeld Strategic Advisors
New York
$2.57M +$371K +10,764 +22%
Susquehanna International Group
75
Susquehanna International Group
Pennsylvania
$2.51M -$217K -6,312 -10%

KYMR Hedge Fund Activity: Q2 2025 in Review

210 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q2 2025, worth a combined $3.44B — up 72% from $2B a quarter earlier.

Buyers outnumbered sellers: 64 funds opened new KYMR positions and 26 closed out — a net gain of 38 holders — while 69 added to existing stakes and 52 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $35.2M. The largest seller was Janus Henderson Group, cutting an estimated $25.9M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q2 2025, up from 173 in Q1 2025.
  • Funds reported $3.44B of Kymera Therapeutics stock for Q2 2025, up 72% quarter-over-quarter.
  • 64 funds opened new Kymera Therapeutics positions in Q2 2025 and 26 closed out, a net change of +38 holders.
  • The largest Kymera Therapeutics buyer in Q2 2025 was Fidelity Investments, an estimated $35.2M added.
  • The largest Kymera Therapeutics seller in Q2 2025 was Janus Henderson Group, an estimated $25.9M sold.

Based on aggregated 13F filings for Q2 2025.