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Kymera Therapeutics

254 hedge funds and large institutions have $6.99B invested in Kymera Therapeutics in 2025 Q4 according to their latest regulatory filings, with 68 funds opening new positions, 97 increasing their positions, 64 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

325% more first-time investments, than exits

New positions opened: 68 | Existing positions closed: 16

53% more capital invested

Capital invested by funds: $4.58B → $6.99B (+$2.41B)

52% more repeat investments, than reductions

Existing positions increased: 97 | Existing positions reduced: 64

21% more funds holding

Funds holding: 210254 (+44)

11.78% more ownership

Funds ownership: 113.1%124.88% (+12%)

8% more funds holding in top 10

Funds holding in top 10: 1213 (+1)

41% less call options, than puts

Call options by funds: $9.18M | Put options by funds: $15.6M

Holders
254
Holders Change
+44
Holders Change %
+20.95%
% of All Funds
3.09%
Holding in Top 10
13
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+8.33%
% of All Funds
0.16%
New
68
Increased
97
Reduced
64
Closed
16
Calls
$9.18M
Puts
$15.6M
Net Calls
-$6.45M
Net Calls Change
-$12M
Name Holding Trade Value Shares
Change
Change in
Stake
Dimensional Fund Advisors
26
Dimensional Fund Advisors
Texas
$48.6M -$7.25M -107,393 -15%
DM
27
Deerfield Management
New York
$43.7M -$749K -11,088 -2%
OCA
28
Octagon Capital Advisors
New York
$41.6M +$11.8M +175,000 +49%
Charles Schwab
29
Charles Schwab
California
$38.7M +$3.86M +57,201 +13%
RSCM
30
Rock Springs Capital Management
Maryland
$38.7M +$3.14M +46,497 +10%
Jennison Associates
31
Jennison Associates
New York
$38.6M -$35.9M -531,074 -52%
Pictet Asset Management
32
Pictet Asset Management
Switzerland
$37.8M +$9.21M +136,382 +39%
Northern Trust
33
Northern Trust
Illinois
$36.3M +$2.02M +29,902 +7%
B
34
Braidwell
Connecticut
$35.3M +$12M +177,567 +64%
Adage Capital Partners
35
Adage Capital Partners
Massachusetts
$33.5M +$13M +192,000 +81%
Two Sigma Advisers
36
Two Sigma Advisers
New York
$29.1M +$94.5K +1,400 +0.4%
Alyeska Investment Group
37
Alyeska Investment Group
Illinois
$28.9M -$16.4M -243,202 -40%
Franklin Resources
38
Franklin Resources
California
$27.6M +$21.8M +322,913 +1,020%
Bank of America
39
Bank of America
North Carolina
$26.4M +$10.3M +152,745 +82%
BCM
40
Boxer Capital Management
California
$25.6M +$675K +10,000 +3%
Massachusetts Financial Services
41
Massachusetts Financial Services
Massachusetts
$22.5M -$9.83M -145,610 -33%
NI
42
Nextech Invest
Switzerland
$21.7M -$4.19M -62,013 -18%
Morgan Stanley
43
Morgan Stanley
New York
$21.3M -$7.01M -103,781 -27%
Two Sigma Investments
44
Two Sigma Investments
New York
$20.7M -$11.1M -164,443 -38%
RI
45
RTW Investments
New York
$18.7M +$16.2M +240,000 New
GGHC
46
Gilder Gagnon Howe & Co
New York
$18.7M -$458K -6,788 -3%
DMC
47
Deer Management Company
New York
$18M -$6.42M -95,084 -29%
TD Asset Management
48
TD Asset Management
Ontario, Canada
$17.2M +$806K +11,930 +6%
FTM
49
First Turn Management
California
$16.1M -$4.81M -71,281 -26%
WP
50
Woodline Partners
California
$15.8M -$3M -44,415 -18%