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Kymera Therapeutics

210 hedge funds and large institutions have $3.44B invested in Kymera Therapeutics in 2025 Q2 according to their latest regulatory filings, with 64 funds opening new positions, 69 increasing their positions, 52 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

219% more call options, than puts

Call options by funds: $10.1M | Put options by funds: $3.16M

146% more first-time investments, than exits

New positions opened: 64 | Existing positions closed: 26

72% more capital invested

Capital invested by funds: $2B → $3.44B (+$1.44B)

44% more funds holding in top 10

Funds holding in top 10: 913 (+4)

33% more repeat investments, than reductions

Existing positions increased: 69 | Existing positions reduced: 52

21% more funds holding

Funds holding: 173210 (+37)

8.82% more ownership

Funds ownership: 112.19%121.01% (+8.8%)

Holders
210
Holders Change
+37
Holders Change %
+21.39%
% of All Funds
2.76%
Holding in Top 10
13
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+44.44%
% of All Funds
0.17%
New
64
Increased
69
Reduced
52
Closed
26
Calls
$10.1M
Puts
$3.16M
Net Calls
+$6.93M
Net Calls Change
+$5.69M
Name Holding Trade Value Shares
Change
Change in
Stake
FCM
26
Frontier Capital Management
Massachusetts
$21.5M +$12.4M +359,847 +273%
Massachusetts Financial Services
27
Massachusetts Financial Services
Massachusetts
$21.3M +$2.34M +67,916 +16%
AIIC
28
AJU IB Investment Company
South Korea
$19.9M
RSCM
29
Rock Springs Capital Management
Maryland
$19.7M -$11.8M -344,063 -43%
BCM
30
Boxer Capital Management
California
$18.9M +$3.68M +107,010 +33%
Charles Schwab
31
Charles Schwab
California
$18.7M +$1.64M +47,596 +12%
Northern Trust
32
Northern Trust
Illinois
$17.9M -$424K -12,307 -3%
NI
33
Nextech Invest
Switzerland
$14.9M +$11.7M +340,909 New
GGHC
34
Gilder Gagnon Howe & Co
New York
$14.4M +$366K +10,639 +3%
DMC
35
Deer Management Company
New York
$14.2M -$3.1M -90,000 -22%
Adage Capital Partners
36
Adage Capital Partners
Massachusetts
$13.3M +$10.5M +304,200 New
Goldman Sachs
37
Goldman Sachs
New York
$12.2M -$2.26M -65,501 -19%
SCM
38
Suvretta Capital Management
New York
$12M +$9.47M +275,000 New
Marshall Wace
39
Marshall Wace
United Kingdom
$11.8M +$2.32M +67,384 +33%
OCA
40
Octagon Capital Advisors
New York
$11.6M +$9.16M +266,000 New
PCH
41
Polar Capital Holdings
United Kingdom
$10.9M +$8.61M +250,000 New
Morgan Stanley
42
Morgan Stanley
New York
$10.4M +$2.26M +65,523 +38%
TD Asset Management
43
TD Asset Management
Ontario, Canada
$10.3M +$1.13M +32,878 +16%
Two Sigma Advisers
44
Two Sigma Advisers
New York
$9.79M +$1.41M +41,000 +22%
PA
45
Perceptive Advisors
New York
$9.17M +$7.23M +210,106 New
JP Morgan Chase
46
JP Morgan Chase
New York
$9.06M +$5.54M +160,848 +343%
Point72 Asset Management
47
Point72 Asset Management
Connecticut
$8.05M +$6.35M +184,478 New
Voloridge Investment Management
48
Voloridge Investment Management
Florida
$7.08M +$623K +18,091 +13%
Two Sigma Investments
49
Two Sigma Investments
New York
$6.95M +$397K +11,543 +8%
Royal Bank of Canada
50
Royal Bank of Canada
Ontario, Canada
$6.82M +$5.31M +154,109 +7,188%

KYMR Hedge Fund Activity: Q2 2025 in Review

210 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Kymera Therapeutics (KYMR) for Q2 2025, worth a combined $3.44B — up 72% from $2B a quarter earlier.

Buyers outnumbered sellers: 64 funds opened new KYMR positions and 26 closed out — a net gain of 38 holders — while 69 added to existing stakes and 52 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $35.2M. The largest seller was Janus Henderson Group, cutting an estimated $25.9M.

  • 210 institutional investors held Kymera Therapeutics (KYMR) as of Q2 2025, up from 173 in Q1 2025.
  • Funds reported $3.44B of Kymera Therapeutics stock for Q2 2025, up 72% quarter-over-quarter.
  • 64 funds opened new Kymera Therapeutics positions in Q2 2025 and 26 closed out, a net change of +38 holders.
  • The largest Kymera Therapeutics buyer in Q2 2025 was Fidelity Investments, an estimated $35.2M added.
  • The largest Kymera Therapeutics seller in Q2 2025 was Janus Henderson Group, an estimated $25.9M sold.

Based on aggregated 13F filings for Q2 2025.