|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$284M
|
+$8.86M
|
+179,374
|
+4%
|
|
|
2
|
|
$153M
|
+$5.9M
|
+119,364
|
+5%
|
|
|
3
|
Alkeon Capital Management
New York
|
$110M
|
+$14.8M
|
+298,694
|
+19%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$108M
|
+$4.9M
|
+99,298
|
+6%
|
|
|
5
|
Darwin Global Management
St. Helier,
Jersey
|
$88.5M
|
-$107K
|
-2,170
|
-0.1%
|
|
|
6
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$87.9M
|
+$16.1M
|
+326,595
|
+27%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$64.7M
|
-$5.32M
|
-107,786
|
-9%
|
|
|
8
|
|
$59.2M
|
-$12.3M
|
-250,000
|
-20%
|
|
|
9
|
Point72 Asset Management
Stamford,
Connecticut
|
$55M
|
+$28.5M
|
+577,220
|
+156%
|
|
|
10
|
TCG Crossover Management
Palo Alto,
California
|
$51.1M
|
–
|
–
|
–
|
|
|
11
|
Jefferies Financial Group
New York
|
$50.3M
|
-$1.6M
|
-32,340
|
-4%
|
|
|
12
|
Holocene Advisors
New York
|
$49M
|
+$7.64M
|
+154,784
|
+22%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$44.3M
|
-$607K
|
-12,297
|
-2%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$42.1M
|
+$2.27M
|
+46,041
|
+7%
|
|
|
15
|
Braidwell
Stamford,
Connecticut
|
$41.1M
|
-$13.6M
|
-274,969
|
-28%
|
|
|
16
|
Citadel Advisors
Miami,
Florida
|
$40.9M
|
+$14.5M
|
+294,439
|
+72%
|
|
|
17
|
Millennium Management
New York
|
$33.3M
|
+$8.89M
|
+180,034
|
+46%
|
|
|
18
|
Redmile Group
San Francisco,
California
|
$32.1M
|
–
|
–
|
–
|
|
|
19
|
Paradigm Biocapital Advisors
New York
|
$30.5M
|
+$25.9M
|
+525,037
|
New
|
|
|
20
|
ADAR1 Capital Management
Austin,
Texas
|
$25.8M
|
-$5.13M
|
-103,848
|
-19%
|
|
|
21
|
Parkman Healthcare Partners
Stamford,
Connecticut
|
$24.5M
|
+$11M
|
+223,155
|
+112%
|
|
|
22
|
Opaleye Management
Boston,
Massachusetts
|
$23M
|
+$1.37M
|
+27,776
|
+8%
|
|
|
23
|
Nantahala Capital Management
New Canaan,
Connecticut
|
$22.2M
|
+$141K
|
+2,852
|
+0.8%
|
|
|
24
|
Eventide Asset Management
Boston,
Massachusetts
|
$22.1M
|
-$5.89M
|
-119,208
|
-24%
|
|
|
25
|
|
$21.2M
|
+$1.46M
|
+29,628
|
+9%
|
|
