|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$332M
|
+$67.9M
|
+1,144,312
|
+30%
|
|
|
2
|
|
$143M
|
+$7.66M
|
+129,222
|
+6%
|
|
|
3
|
Alkeon Capital Management
New York
|
$106M
|
+$5.93M
|
+100,000
|
+7%
|
|
|
4
|
State Street
Boston,
Massachusetts
|
$103M
|
+$30.2M
|
+508,528
|
+48%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$102M
|
+$6.73M
|
+113,563
|
+8%
|
|
|
6
|
Darwin Global Management
St. Helier,
Jersey
|
$95.1M
|
+$22.3M
|
+375,523
|
+35%
|
|
|
7
|
|
$84M
|
–
|
–
|
–
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$80.7M
|
+$10.5M
|
+176,803
|
+17%
|
|
|
9
|
Point72 Asset Management
Stamford,
Connecticut
|
$64.3M
|
+$52.8M
|
+890,651
|
+1,096%
|
|
|
10
|
TCG Crossover Management
Palo Alto,
California
|
$58.2M
|
+$52.1M
|
+879,344
|
New
|
|
|
11
|
Woodline Partners
San Francisco,
California
|
$50.4M
|
+$10.5M
|
+177,908
|
+30%
|
|
|
12
|
Braidwell
Stamford,
Connecticut
|
$48.8M
|
-$22.6M
|
-381,582
|
-34%
|
|
|
13
|
Eventide Asset Management
Boston,
Massachusetts
|
$45M
|
+$5.93M
|
+100,000
|
+17%
|
|
|
14
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$43.2M
|
-$9.91M
|
-167,063
|
-20%
|
|
|
15
|
Holocene Advisors
New York
|
$42.2M
|
+$37.8M
|
+637,983
|
New
|
|
|
16
|
Jefferies Financial Group
New York
|
$41.9M
|
+$36.6M
|
+617,771
|
+3,885%
|
|
|
17
|
Franklin Resources
San Mateo,
California
|
$41.8M
|
-$4M
|
-67,376
|
-10%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$39.5M
|
+$5.08M
|
+85,635
|
+17%
|
|
|
19
|
Redmile Group
San Francisco,
California
|
$36.6M
|
+$32.8M
|
+552,506
|
New
|
|
|
20
|
Citadel Advisors
Miami,
Florida
|
$29.8M
|
-$18.4M
|
-309,890
|
-41%
|
|
|
21
|
Opaleye Management
Boston,
Massachusetts
|
$24.3M
|
+$593K
|
+10,000
|
+3%
|
|
|
22
|
ADAR1 Capital Management
Austin,
Texas
|
$22.4M
|
-$20.8M
|
-350,073
|
-51%
|
|
|
23
|
Millennium Management
New York
|
$22.4M
|
-$10.9M
|
-184,465
|
-35%
|
|
|
24
|
Nantahala Capital Management
New Canaan,
Connecticut
|
$19.5M
|
-$957K
|
-16,144
|
-5%
|
|
|
25
|
|
$19.1M
|
-$37.7M
|
-636,231
|
-69%
|
|
