|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$180M
|
+$18M
|
+283,497
|
+11%
|
|
|
2
|
|
$103M
|
–
|
–
|
–
|
|
|
3
|
Foresite Capital Management IV
Larkspur,
California
|
$85.1M
|
-$1.9M
|
-30,064
|
-2%
|
|
|
4
|
|
$75.3M
|
+$1.57M
|
+24,844
|
+2%
|
|
|
5
|
Consonance Capital Management
New York
|
$54.8M
|
+$21.1M
|
+333,114
|
+60%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$44.6M
|
+$18.9M
|
+297,732
|
+70%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$37.1M
|
+$658K
|
+10,391
|
+2%
|
|
|
8
|
Alkeon Capital Management
New York
|
$32.2M
|
+$83.5K
|
+1,318
|
+0.3%
|
|
|
9
|
Nantahala Capital Management
New Canaan,
Connecticut
|
$28.3M
|
-$4.7M
|
-74,142
|
-14%
|
|
|
10
|
Eventide Asset Management
Boston,
Massachusetts
|
$26.3M
|
+$5.16M
|
+81,414
|
+24%
|
|
|
11
|
|
$24.6M
|
-$2.12M
|
-33,384
|
-8%
|
|
|
12
|
|
$22.9M
|
-$19M
|
-300,000
|
-45%
|
|
|
13
|
Clal Insurance
Tel-Aviv,
Israel
|
$19.7M
|
–
|
–
|
–
|
|
|
14
|
Franklin Resources
San Mateo,
California
|
$16M
|
+$3.36K
|
+53
|
+0%
|
|
|
15
|
Point72 Asset Management
Stamford,
Connecticut
|
$13.7M
|
+$593K
|
+9,362
|
+4%
|
|
|
16
|
|
$11.8M
|
+$108K
|
+1,704
|
+0.9%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$10.7M
|
+$1.05M
|
+16,561
|
+11%
|
|
|
18
|
Opaleye Management
Boston,
Massachusetts
|
$9.69M
|
+$9.98M
|
+157,500
|
New
|
|
|
19
|
Millennium Management
New York
|
$8.02M
|
+$2.68M
|
+42,309
|
+48%
|
|
|
20
|
Citadel Advisors
Miami,
Florida
|
$7.87M
|
-$8.95M
|
-141,318
|
-52%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$7.87M
|
-$467K
|
-7,371
|
-5%
|
|
|
22
|
Nuveen
Charlotte,
North Carolina
|
$7.65M
|
+$1.85M
|
+29,275
|
+31%
|
|
|
23
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$6.73M
|
+$6.93M
|
+109,333
|
New
|
|
|
24
|
Marshall Wace North America
New York
|
$6.65M
|
+$6.85M
|
+108,059
|
New
|
|
|
25
|
Darwin Global Management
St. Helier,
Jersey
|
$5.35M
|
+$5.5M
|
+86,887
|
New
|
|
