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JBIO

Jade Biosciences

105 hedge funds and large institutions have $726M invested in Jade Biosciences in 2025 Q4 according to their latest regulatory filings, with 33 funds opening new positions, 44 increasing their positions, 14 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed

450% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 6

400% more funds holding in top 10

Funds holding in top 10: 15 (+4)

214% more repeat investments, than reductions

Existing positions increased: 44 | Existing positions reduced: 14

166% more capital invested

Capital invested by funds: $273M → $726M (+$453M)

35% more funds holding

Funds holding: 78105 (+27)

1.45% less ownership

Funds ownership: 96.91%95.46% (-1.4%)

100% less call options, than puts

Call options by funds: $3K | Put options by funds: $1.76M

Holders
105
Holders Change
+27
Holders Change %
+34.62%
% of All Funds
1.28%
Holding in Top 10
5
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+400%
% of All Funds
0.06%
New
33
Increased
44
Reduced
14
Closed
6
Calls
$3K
Puts
$1.76M
Net Calls
-$1.75M
Net Calls Change
-$839K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$106M +$23.5M +2,005,707 +41%
FFM
2
Fairmount Funds Management
Pennsylvania
$70.3M +$15.6M +1,333,126 +41%
RCM
3
RA Capital Management
Massachusetts
$56.6M +$30.6M +2,608,757 +246%
BG
4
Bellevue Group
Switzerland
$51.6M +$39.2M +3,341,103 New
VA
5
VR Adviser
New York
$49.7M
BlackRock
6
BlackRock
New York
$44.3M +$8.45M +720,110 +33%
Vanguard Group
7
Vanguard Group
Pennsylvania
$32.3M +$4.33M +369,023 +21%
BBA
8
Baker Bros. Advisors
New York
$25.3M +$19.3M +1,641,137 New
RCP
9
Remedium Capital Partners
Florida
$24.3M +$18.5M +1,577,750 New
VVM
10
Versant Venture Management
California
$23.5M
RI
11
RTW Investments
New York
$22.4M
APM
12
Avidity Partners Management
Texas
$21.6M +$3.21M +273,522 +24%
SB
13
Samsara BioCapital
California
$14.9M +$5.13M +437,635 +82%
DCM
14
Driehaus Capital Management
Illinois
$13.7M -$4.32M -368,619 -29%
Marshall Wace
15
Marshall Wace
United Kingdom
$13.5M +$9.82M +837,193 +2,199%
Aberdeen Group
16
Aberdeen Group
United Kingdom
$13.4M +$10.2M +867,284 New
Geode Capital Management
17
Geode Capital Management
Massachusetts
$13M +$2.06M +175,893 +26%
GPP
18
Great Point Partners
Connecticut
$12.4M +$2.04M +173,674 +27%
SCM
19
Soleus Capital Management
Connecticut
$12.3M
AAA
20
Affinity Asset Advisors
New York
$11M +$7.62M +649,639 +995%
State Street
21
State Street
Massachusetts
$9.92M +$1.68M +143,634 +29%
Point72 Asset Management
22
Point72 Asset Management
Connecticut
$8.62M +$6.55M +558,474 New
O
23
OrbiMed
New York
$8.2M
OM
24
Opaleye Management
Massachusetts
$6.6M +$5.02M +427,608 New
LGM
25
Logos Global Management
California
$6.09M -$2.7M -230,000 -37%