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JBIO

Jade Biosciences

75 hedge funds and large institutions have $315M invested in Jade Biosciences in 2025 Q2 according to their latest regulatory filings, with 27 funds opening new positions, 40 increasing their positions, 4 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

3,798.79% more ownership

Funds ownership: 3.12%3,801.92% (+3,799%)

900% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 4

296% more capital invested

Capital invested by funds: $79.6M → $315M (+$236M)

4% less funds holding

Funds holding: 7875 (-3)

10% less first-time investments, than exits

New positions opened: 27 | Existing positions closed: 30

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

100% less call options, than puts

Call options by funds: $0 | Put options by funds: $1.52M

Holders
75
Holders Change
-3
Holders Change %
-3.85%
% of All Funds
0.99%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
27
Increased
40
Reduced
4
Closed
30
Calls
Puts
$1.52M
Net Calls
-$1.52M
Net Calls Change
-$1.44M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$48.3M +$165M +4,834,990 +1,230,277%
FFM
2
Fairmount Funds Management
Pennsylvania
$32.2M +$110M +3,220,368 New
VA
3
VR Adviser
New York
$32.2M +$110M +3,220,364 New
DTC
4
Deep Track Capital
Connecticut
$25.1M +$85.4M +2,509,301 New
Vanguard Group
5
Vanguard Group
Pennsylvania
$18.1M +$60.5M +1,777,096 +5,829%
FLSM
6
Frazier Life Sciences Management
California
$17.7M +$60.3M +1,772,116 New
BlackRock
7
BlackRock
New York
$17.1M +$57.4M +1,686,940 +6,155%
VVM
8
Versant Venture Management
California
$15.2M +$51.9M +1,525,820 New
RI
9
RTW Investments
New York
$14.5M +$49.3M +1,449,273 New
DCM
10
Driehaus Capital Management
Illinois
$12.5M +$42.7M +1,255,798 New
APM
11
Avidity Partners Management
Texas
$11.3M +$38.4M +1,127,186 New
RCM
12
RA Capital Management
Massachusetts
$10.6M +$27.2M +799,695 +304%
SCM
13
Soleus Capital Management
Connecticut
$7.96M +$27.1M +796,744 New
Geode Capital Management
14
Geode Capital Management
Massachusetts
$6.76M +$22.7M +668,000 +7,923%
LGM
15
Logos Global Management
California
$6.24M +$19.9M +585,000 +1,463%
DM
16
Deerfield Management
New York
$5.31M +$18.1M +531,163 New
O
17
OrbiMed
New York
$5.31M +$18.1M +531,163 New
SB
18
Samsara BioCapital
California
$5.31M +$18.1M +531,163 New
GPP
19
Great Point Partners
Connecticut
$4.98M +$17M +498,054 New
State Street
20
State Street
Massachusetts
$3.18M +$10.5M +308,241 +2,927%
Barclays
21
Barclays
United Kingdom
$2.75M +$9.34M +274,413 +65,806%
Northern Trust
22
Northern Trust
Illinois
$2.28M +$7.66M +224,972 +7,211%
SI
23
Sofinnova Investments
California
$1.07M
WP
24
Woodline Partners
California
$1.06M +$3.62M +106,270 New
Charles Schwab
25
Charles Schwab
California
$1.03M +$3.49M +102,416 +12,207%

JBIO Hedge Fund Activity: Q2 2025 in Review

75 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Jade Biosciences (JBIO) for Q2 2025, worth a combined $315M — up 296% from $79.6M a quarter earlier.

Sellers outnumbered buyers: 30 funds closed out of JBIO and 27 opened new positions — a net loss of 3 holders — while 4 trimmed existing stakes and 40 added.

The largest buyer was Fidelity Investments, adding an estimated $165M. The largest seller was Atlas Venture Life Science Advisors, exiting entirely with an estimated $4.52M sold.

  • 75 institutional investors held Jade Biosciences (JBIO) as of Q2 2025, down from 78 in Q1 2025.
  • Funds reported $315M of Jade Biosciences stock for Q2 2025, up 296% quarter-over-quarter.
  • 27 funds opened new Jade Biosciences positions in Q2 2025 and 30 closed out, a net change of -3 holders.
  • The largest Jade Biosciences buyer in Q2 2025 was Fidelity Investments, an estimated $165M added.
  • The largest Jade Biosciences seller in Q2 2025 was Atlas Venture Life Science Advisors, an estimated $4.52M sold.

Based on aggregated 13F filings for Q2 2025.