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Janux Therapeutics

174 hedge funds and large institutions have $1.59B invested in Janux Therapeutics in 2025 Q3 according to their latest regulatory filings, with 22 funds opening new positions, 57 increasing their positions, 64 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

172% more call options, than puts

Call options by funds: $14.6M | Put options by funds: $5.39M

5% more capital invested

Capital invested by funds: $1.51B → $1.59B (+$78.5M)

0% more funds holding

Funds holding: 174174 (0)

0% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 22

2.17% less ownership

Funds ownership: 110.61%108.44% (-2.2%)

11% less repeat investments, than reductions

Existing positions increased: 57 | Existing positions reduced: 64

40% less funds holding in top 10

Funds holding in top 10: 53 (-2)

Holders
174
Holders Change
Holders Change %
0%
% of All Funds
2.28%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
22
Increased
57
Reduced
64
Closed
22
Calls
$14.6M
Puts
$5.39M
Net Calls
+$9.26M
Net Calls Change
+$4.19M
Name Holding Trade Value Shares
Change
Change in
Stake
RPAM
51
Rhenman & Partners Asset Management
Sweden
$2.45M +$1.1M +45,000 +82%
Tudor Investment Corp
52
Tudor Investment Corp
Connecticut
$2.41M -$370K -15,193 -13%
Lazard Asset Management
53
Lazard Asset Management
New York
$2.38M -$58.1K -2,385 -2%
N
54
Nuveen
North Carolina
$2.34M -$8.43K -346 -0.4%
TD Asset Management
55
TD Asset Management
Ontario, Canada
$2.26M +$659K +27,066 +41%
CM
56
Caption Management
Oklahoma
$2.2M -$8.94M -367,012 -80%
AG
57
Algert Global
California
$2.16M -$104K -4,265 -5%
SFM
58
Sphera Funds Management
Israel
$2.1M
DekaBank Deutsche Girozentrale
59
DekaBank Deutsche Girozentrale
Germany
$2.02M
Jane Street
60
Jane Street
New York
$1.99M +$1.16M +47,509 +141%
Macquarie Group
61
Macquarie Group
Australia
$1.87M
Rafferty Asset Management
62
Rafferty Asset Management
New York
$1.86M +$713K +29,267 +62%
Swiss National Bank
63
Swiss National Bank
Switzerland
$1.82M -$110K -4,500 -6%
UBS AM
64
UBS AM
Illinois
$1.62M -$1.1M -45,037 -40%
Squarepoint
65
Squarepoint
New York
$1.62M -$3.01M -123,408 -65%
Manulife (Manufacturers Life Insurance)
66
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.59M -$237K -9,752 -13%
QOP
67
Quinn Opportunity Partners
Virginia
$1.46M
RhumbLine Advisers
68
RhumbLine Advisers
Massachusetts
$1.41M -$42.5K -1,747 -3%
CAM
69
Congress Asset Management
Massachusetts
$1.36M +$1.36M +55,773 New
HS
70
HighVista Strategies
Massachusetts
$1.35M -$175K -7,186 -12%
IC
71
Ikarian Capital
Texas
$1.34M -$1.83M -75,000 -58%
AVM
72
Avalon Ventures Management
California
$1.3M +$244K +10,000 +23%
Hudson Bay Capital Management
73
Hudson Bay Capital Management
Connecticut
$1.22M +$487K +20,000 +67%
Verition Fund Management
74
Verition Fund Management
Connecticut
$995K +$700K +28,761 +240%
NIM
75
NEOS Investment Management
Connecticut
$986K -$237K -9,714 -19%

JANX Hedge Fund Activity: Q3 2025 in Review

174 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Janux Therapeutics (JANX) for Q3 2025, worth a combined $1.59B — up 5.2% from $1.51B a quarter earlier.

Fund positioning in JANX was balanced in Q3 2025: 22 funds opened new positions, 22 closed out, 57 added to existing stakes and 64 trimmed.

The largest buyer was T. Rowe Price Investment Management, opening a new position worth an estimated $23.7M. The largest seller was EcoR1 Capital, exiting entirely with an estimated $34M sold.

  • 174 institutional investors held Janux Therapeutics (JANX) as of Q3 2025, unchanged from Q2 2025.
  • Funds reported $1.59B of Janux Therapeutics stock for Q3 2025, up 5.2% quarter-over-quarter.
  • 22 funds opened new Janux Therapeutics positions in Q3 2025 and 22 closed out, a net change of 0 holders.
  • The largest Janux Therapeutics buyer in Q3 2025 was T. Rowe Price Investment Management, an estimated $23.7M added.
  • The largest Janux Therapeutics seller in Q3 2025 was EcoR1 Capital, an estimated $34M sold.

Based on aggregated 13F filings for Q3 2025.