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Janux Therapeutics

174 hedge funds and large institutions have $1.51B invested in Janux Therapeutics in 2025 Q2 according to their latest regulatory filings, with 16 funds opening new positions, 80 increasing their positions, 54 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

48% more repeat investments, than reductions

Existing positions increased: 80 | Existing positions reduced: 54

34% more call options, than puts

Call options by funds: $20.2M | Put options by funds: $15.1M

1.86% less ownership

Funds ownership: 112.47%110.61% (-1.9%)

4% less funds holding

Funds holding: 181174 (-7)

16% less capital invested

Capital invested by funds: $1.81B → $1.51B (-$292M)

27% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 22

29% less funds holding in top 10

Funds holding in top 10: 75 (-2)

Holders
174
Holders Change
-7
Holders Change %
-3.87%
% of All Funds
2.29%
Holding in Top 10
5
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-28.57%
% of All Funds
0.07%
New
16
Increased
80
Reduced
54
Closed
22
Calls
$20.2M
Puts
$15.1M
Net Calls
+$5.07M
Net Calls Change
-$7.75M
Name Holding Trade Value Shares
Change
Change in
Stake
Dimensional Fund Advisors
51
Dimensional Fund Advisors
Texas
$3.2M +$3.21M +121,711 +718%
Barclays
52
Barclays
United Kingdom
$3.06M +$1.7M +64,575 +95%
IC
53
Ikarian Capital
Texas
$3M
Bank of New York Mellon
54
Bank of New York Mellon
New York
$2.65M +$667K +25,329 +28%
Tudor Investment Corp
55
Tudor Investment Corp
Connecticut
$2.63M -$1.6M -60,601 -35%
UBS AM
56
UBS AM
Illinois
$2.57M -$1.98M -75,032 -40%
Two Sigma Investments
57
Two Sigma Investments
New York
$2.41M +$2.75M +104,382 New
Lazard Asset Management
58
Lazard Asset Management
New York
$2.31M +$1.03M +39,278 +65%
TI
59
Trexquant Investment
Connecticut
$2.22M -$1.92M -72,798 -43%
N
60
Nuveen
North Carolina
$2.22M -$730K -27,704 -22%
AG
61
Algert Global
California
$2.14M +$1.37M +51,822 +127%
SC
62
Stempoint Capital
New York
$2.08M -$6.64M -252,129 -74%
DekaBank Deutsche Girozentrale
63
DekaBank Deutsche Girozentrale
Germany
$2.04M
SFM
64
Sphera Funds Management
Israel
$1.98M -$1.05M -40,000 -32%
TC
65
TwinBeech Capital
New York
$1.89M +$117K +4,445 +6%
Swiss National Bank
66
Swiss National Bank
Switzerland
$1.83M
Macquarie Group
67
Macquarie Group
Australia
$1.77M
Manulife (Manufacturers Life Insurance)
68
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.73M +$158K +5,995 +9%
ECM
69
ExodusPoint Capital Management
New York
$1.73M +$1.23M +46,751 +167%
State of Wisconsin Investment Board
70
State of Wisconsin Investment Board
Wisconsin
$1.62M +$508K +19,297 +38%
TD Asset Management
71
TD Asset Management
Ontario, Canada
$1.51M -$10.5K -400 -0.6%
HS
72
HighVista Strategies
Massachusetts
$1.44M -$319K -12,120 -16%
ACM
73
ADAR1 Capital Management
Texas
$1.43M -$2.42M -91,679 -60%
QOP
74
Quinn Opportunity Partners
Virginia
$1.38M +$211K +8,000 +15%
RhumbLine Advisers
75
RhumbLine Advisers
Massachusetts
$1.37M +$441K +16,741 +39%

JANX Hedge Fund Activity: Q2 2025 in Review

174 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Janux Therapeutics (JANX) for Q2 2025, worth a combined $1.51B — down 16% from $1.81B a quarter earlier.

Sellers outnumbered buyers: 22 funds closed out of JANX and 16 opened new positions — a net loss of 6 holders — while 54 trimmed existing stakes and 80 added.

The largest buyer was Point72 Asset Management, adding an estimated $46.6M. The largest seller was Adage Capital Partners, cutting an estimated $29.8M.

  • 174 institutional investors held Janux Therapeutics (JANX) as of Q2 2025, down from 181 in Q1 2025.
  • Funds reported $1.51B of Janux Therapeutics stock for Q2 2025, down 16% quarter-over-quarter.
  • 16 funds opened new Janux Therapeutics positions in Q2 2025 and 22 closed out, a net change of -6 holders.
  • The largest Janux Therapeutics buyer in Q2 2025 was Point72 Asset Management, an estimated $46.6M added.
  • The largest Janux Therapeutics seller in Q2 2025 was Adage Capital Partners, an estimated $29.8M sold.

Based on aggregated 13F filings for Q2 2025.