|
1
|
Novo Holdings A/S
Hellerup,
Denmark
|
$265M
|
-$41.8M
|
-995,000
|
-14%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$226M
|
+$4.72M
|
+112,449
|
+2%
|
|
|
3
|
JHL Capital Group
Chicago,
Illinois
|
$147M
|
+$8.19M
|
+195,000
|
+6%
|
|
|
4
|
SV Health Investors
Boston,
Massachusetts
|
$118M
|
-$28.9M
|
-687,120
|
-21%
|
|
|
5
|
Clarus Ventures
Cambridge,
Massachusetts
|
$69.8M
|
–
|
–
|
–
|
|
|
6
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$61.5M
|
+$70.1K
|
+1,668
|
+0.1%
|
|
|
7
|
Eagle Asset Management
St Petersburg,
Florida
|
$60.7M
|
-$65.5K
|
-1,560
|
-0.1%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$55M
|
+$11.3M
|
+268,052
|
+28%
|
|
|
9
|
|
$38.7M
|
+$22M
|
+523,000
|
+154%
|
|
|
10
|
|
$35.3M
|
+$15.3M
|
+364,334
|
+86%
|
|
|
11
|
BlackRock Fund Advisors
San Francisco,
California
|
$33.4M
|
+$18.7M
|
+445,368
|
+149%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$24.7M
|
-$1.53M
|
-36,401
|
-6%
|
|
|
13
|
Perceptive Advisors
New York
|
$19.3M
|
-$3.81M
|
-90,779
|
-17%
|
|
|
14
|
Allianz Asset Management
Munich,
Germany
|
$14.8M
|
+$4.67M
|
+111,205
|
+51%
|
|
|
15
|
RA Capital Management
Boston,
Massachusetts
|
$13.9M
|
-$11.7M
|
-278,387
|
-47%
|
|
|
16
|
Stifel Financial
St. Louis,
Missouri
|
$12.8M
|
+$7.72M
|
+183,828
|
New
|
|
|
17
|
|
$12.1M
|
+$1.46M
|
+34,702
|
+15%
|
|
|
18
|
BlackRock Institutional Trust
San Francisco,
California
|
$6.49M
|
-$81.5K
|
-1,941
|
-1%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$6.39M
|
-$205K
|
-4,870
|
-3%
|
|
|
20
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$6.1M
|
+$5.71M
|
+136,000
|
New
|
|
|
21
|
Cupps Capital Management
Chicago,
Illinois
|
$5.69M
|
+$4.16M
|
+99,126
|
+358%
|
|
|
22
|
Millennium Management
New York
|
$4.83M
|
+$4.2M
|
+99,988
|
+1,303%
|
|
|
23
|
Opaleye Management
Boston,
Massachusetts
|
$4.49M
|
+$2.73M
|
+65,000
|
+186%
|
|
|
24
|
Bank of New York Mellon
New York
|
$4.45M
|
+$344K
|
+8,193
|
+9%
|
|
|
25
|
Apex Capital Management
Dayton,
Ohio
|
$4.35M
|
+$972K
|
+23,144
|
+31%
|
|
