|
1
|
State Street
Boston,
Massachusetts
|
$84M
|
+$35.7M
|
+2,843,747
|
+48%
|
|
|
2
|
Janus Henderson Group
London,
|
$78.4M
|
+$84.2M
|
+6,704,654
|
+464%
|
|
|
3
|
|
$77.4M
|
-$4.82M
|
-383,656
|
-5%
|
|
|
4
|
Avoro Capital Advisors
New York
|
$68.5M
|
-$1.63M
|
-130,000
|
-2%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$57.5M
|
+$2.55M
|
+203,187
|
+4%
|
|
|
6
|
Vivo Capital
Palo Alto,
California
|
$50.4M
|
-$15M
|
-1,193,306
|
-19%
|
|
|
7
|
Deerfield Management
New York
|
$50.2M
|
+$4.04M
|
+322,004
|
+7%
|
|
|
8
|
Yiheng Capital Management
San Francisco,
California
|
$48.7M
|
–
|
–
|
–
|
|
|
9
|
Deep Track Capital
Greenwich,
Connecticut
|
$43.3M
|
–
|
–
|
–
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$32.6M
|
-$15.3M
|
-1,220,136
|
-26%
|
|
|
11
|
TCG Crossover Management
Palo Alto,
California
|
$28M
|
+$4.99M
|
+397,330
|
+16%
|
|
|
12
|
Capital International Investors
Los Angeles,
California
|
$25.8M
|
+$33.7M
|
+2,682,230
|
New
|
|
|
13
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$23.3M
|
+$29.1M
|
+2,317,598
|
+2,234%
|
|
|
14
|
Commodore Capital
New York
|
$23.2M
|
+$2.45M
|
+195,000
|
+9%
|
|
|
15
|
Perceptive Advisors
New York
|
$20.1M
|
-$39.4M
|
-3,137,459
|
-60%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$19.1M
|
-$57.4K
|
-4,572
|
-0.2%
|
|
|
17
|
Polar Capital Holdings
London,
United Kingdom
|
$18M
|
–
|
–
|
–
|
|
|
18
|
Two Sigma Advisers
New York
|
$15.7M
|
+$4.44M
|
+353,700
|
+28%
|
|
|
19
|
Millennium Management
New York
|
$15.5M
|
+$4.35M
|
+346,536
|
+27%
|
|
|
20
|
Redmile Group
San Francisco,
California
|
$14.6M
|
+$415K
|
+33,100
|
+2%
|
|
|
21
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$14.1M
|
+$6.1M
|
+485,620
|
+50%
|
|
|
22
|
Two Sigma Investments
New York
|
$13.3M
|
+$5.73M
|
+456,631
|
+49%
|
|
|
23
|
|
$13.1M
|
+$17.1M
|
+1,361,400
|
New
|
|
|
24
|
Dimensional Fund Advisors
Austin,
Texas
|
$12.6M
|
+$3.26M
|
+260,041
|
+25%
|
|
|
25
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$12.4M
|
+$2.46M
|
+196,377
|
+18%
|
|
