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Iovance Biotherapeutics

264 hedge funds and large institutions have $715M invested in Iovance Biotherapeutics in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 103 increasing their positions, 64 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

103% more call options, than puts

Call options by funds: $12M | Put options by funds: $5.94M

61% more repeat investments, than reductions

Existing positions increased: 103 | Existing positions reduced: 64

55% more capital invested

Capital invested by funds: $462M → $715M (+$253M)

46% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 35

7.03% more ownership

Funds ownership: 58.87%65.9% (+7%)

4% more funds holding

Funds holding: 253264 (+11)

33% less funds holding in top 10

Funds holding in top 10: 32 (-1)

Holders
264
Holders Change
+11
Holders Change %
+4.35%
% of All Funds
3.21%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.02%
New
51
Increased
103
Reduced
64
Closed
35
Calls
$12M
Puts
$5.94M
Net Calls
+$6.1M
Net Calls Change
+$3.1M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$80.6M +$8.24M +3,561,836 +14%
MFM
2
MHR Fund Management
New York
$79.1M
Vanguard Group
3
Vanguard Group
Pennsylvania
$74.3M +$7.28M +3,148,096 +13%
State Street
4
State Street
Massachusetts
$55M +$15.9M +6,851,486 +51%
Bank of America
5
Bank of America
North Carolina
$39M +$18.5M +7,998,583 +127%
ICM
6
Invenomic Capital Management
Massachusetts
$32.6M +$3.28M +1,417,897 +13%
Morgan Stanley
7
Morgan Stanley
New York
$25.1M +$8.35M +3,610,277 +65%
Goldman Sachs
8
Goldman Sachs
New York
$23.5M +$4.7M +2,032,062 +31%
LFCM
9
Long Focus Capital Management
Puerto Rico
$23.5M -$1.19M -516,507 -6%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$21.8M +$2.6M +1,123,337 +16%
PAI
11
Palo Alto Investors
California
$19.4M -$1.16M -501,456 -7%
Millennium Management
12
Millennium Management
New York
$18M +$5.02M +2,172,081 +49%
Susquehanna International Group
13
Susquehanna International Group
Pennsylvania
$13.5M +$3.8M +1,642,098 +50%
Two Sigma Investments
14
Two Sigma Investments
New York
$12M +$3.83M +1,657,135 +60%
HF
15
HRT Financial
New York
$11.9M +$9.22M +3,986,314 +1,078%
D.E. Shaw & Co
16
D.E. Shaw & Co
New York
$10.5M +$8.68M +3,753,586 +4,925%
Jane Street
17
Jane Street
New York
$9.78M +$5.02M +2,170,148 +154%
Citadel Advisors
18
Citadel Advisors
Florida
$8.58M -$1.57M -677,273 -18%
Two Sigma Advisers
19
Two Sigma Advisers
New York
$8.23M +$4.53M +1,956,000 +185%
JP Morgan Chase
20
JP Morgan Chase
New York
$8.19M +$4.11M +1,777,671 +145%
Charles Schwab
21
Charles Schwab
California
$7.52M +$576K +248,801 +10%
Northern Trust
22
Northern Trust
Illinois
$7.04M +$274K +118,521 +5%
Wells Fargo
23
Wells Fargo
California
$5.44M +$1.1M +475,973 +31%
OIC
24
Orion Investment Company
Missouri
$5.07M +$11.9K +5,150 +0.3%
RPAM
25
Rhenman & Partners Asset Management
Sweden
$4.36M +$1.15M +497,500 +45%