We are live on ! Find out more
IOVA icon

Iovance Biotherapeutics

301 hedge funds and large institutions have $799M invested in Iovance Biotherapeutics in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 100 increasing their positions, 93 reducing their positions, and 54 closing their positions.

New
Increased
Maintained
Reduced
Closed

25% more call options, than puts

Call options by funds: $8.21M | Put options by funds: $6.57M

8% more repeat investments, than reductions

Existing positions increased: 100 | Existing positions reduced: 93

4% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 54

0% more funds holding

Funds holding: 301301 (0)

6.13% less ownership

Funds ownership: 79.26%73.13% (-6.1%)

55% less capital invested

Capital invested by funds: $1.79B → $799M (-$989M)

71% less funds holding in top 10

Funds holding in top 10: 72 (-5)

Holders
301
Holders Change
Holders Change %
0%
% of All Funds
4.04%
Holding in Top 10
2
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-71.43%
% of All Funds
0.03%
New
56
Increased
100
Reduced
93
Closed
54
Calls
$8.21M
Puts
$6.57M
Net Calls
+$1.64M
Net Calls Change
+$9.18M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$92.5M +$1.26M +243,438 +0.9%
MFM
2
MHR Fund Management
New York
$81.3M
BlackRock
3
BlackRock
New York
$81M +$4.32M +838,543 +4%
PA
4
Perceptive Advisors
New York
$42.3M -$48.5M -9,400,478 -43%
State Street
5
State Street
Massachusetts
$36.8M -$6.23M -1,207,960 -10%
LFCM
6
Long Focus Capital Management
Puerto Rico
$30.8M +$21.2M +4,118,055 +80%
HRCM
7
Hood River Capital Management
Florida
$30.7M +$1.16M +224,467 +2%
SCM
8
Soleus Capital Management
Connecticut
$25.9M +$6.32M +1,225,000 +19%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$19.9M +$500K +96,878 +2%
UBS AM
10
UBS AM
Illinois
$19.2M +$20M +3,869,617 +203%
Goldman Sachs
11
Goldman Sachs
New York
$18.6M +$7.54M +1,461,846 +36%
ICM
12
Invenomic Capital Management
Massachusetts
$18.3M +$28.3M +5,489,799 New
Macquarie Group
13
Macquarie Group
Australia
$16M +$208K +40,301 +0.8%
Principal Financial Group
14
Principal Financial Group
Iowa
$15.6M +$5.4M +1,047,335 +29%
Artisan Partners
15
Artisan Partners
Wisconsin
$14.7M -$693K -134,455 -3%
Morgan Stanley
16
Morgan Stanley
New York
$13.4M +$302K +58,535 +1%
Renaissance Technologies
17
Renaissance Technologies
New York
$11.7M +$18.1M +3,511,400 New
Dimensional Fund Advisors
18
Dimensional Fund Advisors
Texas
$11.7M +$5.55M +1,075,887 +44%
PAI
19
Palo Alto Investors
California
$10.7M +$875K +169,629 +6%
Bank of America
20
Bank of America
North Carolina
$10M +$11.7M +2,275,767 +307%
MB
21
MPM BioImpact
Massachusetts
$9.02M +$179K +34,677 +1%
UBS Group
22
UBS Group
Switzerland
$8.31M -$1.07M -207,720 -8%
T. Rowe Price Associates
23
T. Rowe Price Associates
Maryland
$8.01M -$1.16M -224,021 -9%
6CM
24
683 Capital Management
New York
$7.99M +$5.07M +983,986 +69%
Northern Trust
25
Northern Trust
Illinois
$7.8M -$367K -71,244 -3%

IOVA Hedge Fund Activity: Q1 2025 in Review

301 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Iovance Biotherapeutics (IOVA) for Q1 2025, worth a combined $799M — down 55% from $1.79B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new IOVA positions and 54 closed out — a net gain of 2 holders — while 100 added to existing stakes and 93 trimmed.

The largest buyer was Invenomic Capital Management, opening a new position worth an estimated $28.3M. The largest seller was Perceptive Advisors, cutting an estimated $48.5M.

  • 301 institutional investors held Iovance Biotherapeutics (IOVA) as of Q1 2025, unchanged from Q4 2024.
  • Funds reported $799M of Iovance Biotherapeutics stock for Q1 2025, down 55% quarter-over-quarter.
  • 56 funds opened new Iovance Biotherapeutics positions in Q1 2025 and 54 closed out, a net change of +2 holders.
  • The largest Iovance Biotherapeutics buyer in Q1 2025 was Invenomic Capital Management, an estimated $28.3M added.
  • The largest Iovance Biotherapeutics seller in Q1 2025 was Perceptive Advisors, an estimated $48.5M sold.

Based on aggregated 13F filings for Q1 2025.