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Iovance Biotherapeutics
IOVA

Overview Fund Activity

248 hedge funds and large institutions have $379M invested in Iovance Biotherapeutics in 2025 Q2 according to their latest regulatory filings, with 37 funds opening new positions, 92 increasing their positions, 72 reducing their positions, and 82 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
248
Holders Change
-52
Holders Change %
-17.33%
% of All Funds
3.33%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
37
Increased
92
Reduced
72
Closed
82
Calls
$3.58M
Puts
$2.55M
Net Calls
+$1.03M
Net Calls Change
-$284K

Top Buyers

1
Millennium Management
Millennium Management
New York
$16M
2
MFM
MHR Fund Management
New York
$49.8M
3
Two Sigma Investments
Two Sigma Investments
New York
$7.97M
4
ICM
Invenomic Capital Management
Massachusetts
$14.3M
5
LFCM
Long Focus Capital Management
Puerto Rico
$20.3M

Top Sellers

1
PA
Perceptive Advisors
New York
$0
2
HRCM
Hood River Capital Management
Florida
$0
3
Macquarie Group
Macquarie Group
Australia
$0
4
Artisan Partners
Artisan Partners
Wisconsin
$0
5
MB
MPM BioImpact
Massachusetts
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
MFM
1
MHR Fund Management
New York
$49.8M +$7.83M +4,550,000 +19%
Vanguard Group
2
Vanguard Group
Pennsylvania
$43.1M -$4.65M -2,701,306 -10%
BlackRock
3
BlackRock
New York
$40M -$1.85M -1,077,766 -4%
LFCM
4
Long Focus Capital Management
Puerto Rico
$20.3M +$4.42M +2,569,945 +28%
State Street
5
State Street
Massachusetts
$17M -$1.98M -1,150,797 -10%
Millennium Management
6
Millennium Management
New York
$16M +$15.8M +9,171,900 +5,793%
ICM
7
Invenomic Capital Management
Massachusetts
$14.3M +$4.82M +2,804,864 +51%
Morgan Stanley
8
Morgan Stanley
New York
$11.1M +$4.18M +2,432,559 +61%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$10.6M +$380K +220,760 +4%
Renaissance Technologies
10
Renaissance Technologies
New York
$8.41M +$2.37M +1,375,800 +39%
Goldman Sachs
11
Goldman Sachs
New York
$8.17M -$1.41M -822,026 -15%
Two Sigma Investments
12
Two Sigma Investments
New York
$7.97M +$7.29M +4,236,457 +1,067%
Principal Financial Group
13
Principal Financial Group
Iowa
$7.91M -$159K -92,681 -2%
Citadel Advisors
14
Citadel Advisors
Florida
$7.08M +$4.09M +2,380,785 +137%
Bank of America
15
Bank of America
North Carolina
$6.93M +$1.74M +1,012,383 +34%
PAI
16
Palo Alto Investors
California
$5.9M +$375K +218,015 +7%
SCM
17
Soleus Capital Management
Connecticut
$5.61M -$7.78M -4,523,293 -58%
Dimensional Fund Advisors
18
Dimensional Fund Advisors
Texas
$5.04M -$993K -577,372 -16%
Royal Bank of Canada
19
Royal Bank of Canada
Ontario, Canada
$4.09M +$3.19M +1,856,201 +355%
OIC
20
Orion Investment Company
Missouri
$4.02M +$2M +1,161,710 +99%
Two Sigma Advisers
21
Two Sigma Advisers
New York
$4.02M +$4.02M +2,334,900 New
Northern Trust
22
Northern Trust
Illinois
$3.65M -$385K -223,776 -10%
T. Rowe Price Associates
23
T. Rowe Price Associates
Maryland
$3.64M -$499K -289,890 -12%
Susquehanna International Group
24
Susquehanna International Group
Pennsylvania
$3.56M +$463K +269,279 +15%
Jane Street
25
Jane Street
New York
$3.45M +$3.24M +1,886,481 +1,558%
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