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Iovance Biotherapeutics

301 hedge funds and large institutions have $799M invested in Iovance Biotherapeutics in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 100 increasing their positions, 93 reducing their positions, and 54 closing their positions.

New
Increased
Maintained
Reduced
Closed

25% more call options, than puts

Call options by funds: $8.21M | Put options by funds: $6.57M

8% more repeat investments, than reductions

Existing positions increased: 100 | Existing positions reduced: 93

4% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 54

0% more funds holding

Funds holding: 301301 (0)

6.13% less ownership

Funds ownership: 79.26%73.13% (-6.1%)

55% less capital invested

Capital invested by funds: $1.79B → $799M (-$989M)

71% less funds holding in top 10

Funds holding in top 10: 72 (-5)

Holders
301
Holders Change
Holders Change %
0%
% of All Funds
4.04%
Holding in Top 10
2
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-71.43%
% of All Funds
0.03%
New
56
Increased
100
Reduced
93
Closed
54
Calls
$8.21M
Puts
$6.57M
Net Calls
+$1.64M
Net Calls Change
+$9.18M
Name Holding Trade Value Shares
Change
Change in
Stake
RAM
151
Roanoke Asset Management
New Jersey
$134K
IFO
152
Intrepid Family Office
Florida
$133K +$51.6K +10,000 +33%
Marshall Wace
153
Marshall Wace
United Kingdom
$132K -$5.63M -1,090,813 -96%
EFM
154
E Fund Management
China
$131K -$232 -45 -0.1%
D.E. Shaw & Co
155
D.E. Shaw & Co
New York
$131K +$43.7K +8,464 +27%
TIA
156
Traphagen Investment Advisors
New Jersey
$128K +$8.65K +1,678 +5%
CPIG
157
Chicago Partners Investment Group
Illinois
$127K +$103K +20,067 +98%
Man Group
158
Man Group
United Kingdom
$126K -$12.3M -2,377,238 -98%
CHAM
159
Clear Harbor Asset Management
Connecticut
$117K +$60.3K +11,700 +50%
ETC
160
Exchange Traded Concepts
Oklahoma
$113K +$87.6K +16,990 +100%
Neuberger Berman Group
161
Neuberger Berman Group
New York
$113K +$45.8K +8,879 +35%
Cetera Investment Advisers
162
Cetera Investment Advisers
Illinois
$112K +$40.3K +7,814 +30%
QC
163
Quadrature Capital
United Kingdom
$109K +$169K +32,732 New
Mitsubishi UFJ Asset Management
164
Mitsubishi UFJ Asset Management
Japan
$108K +$14K +2,715 +9%
GC
165
Grimes & Company
Massachusetts
$107K -$7.52K -1,458 -4%
Victory Capital Management
166
Victory Capital Management
Texas
$107K -$564K -109,429 -77%
VRS
167
Virginia Retirement Systems
Virginia
$103K +$160K +31,000 New
CIM
168
CIM Investment Management
Pennsylvania
$101K -$3.74K -726 -2%
Wolverine Trading
169
Wolverine Trading
Illinois
$99.7K -$69.8K -13,532 -33%
APP
170
Avantax Planning Partners
Iowa
$98.6K +$34K +6,600 +29%
AIP
171
Ameritas Investment Partners
Nebraska
$95.7K
PHS
172
Pekin Hardy Strauss
Illinois
$93.4K
Wealth Enhancement Advisory Services
173
Wealth Enhancement Advisory Services
Minnesota
$91.4K +$44.9K +8,713 +46%
FCM
174
Farallon Capital Management
California
$86.6K
Janney Montgomery Scott
175
Janney Montgomery Scott
Pennsylvania
$86K -$12.6K -2,439 -9%

IOVA Hedge Fund Activity: Q1 2025 in Review

301 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Iovance Biotherapeutics (IOVA) for Q1 2025, worth a combined $799M — down 55% from $1.79B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new IOVA positions and 54 closed out — a net gain of 2 holders — while 100 added to existing stakes and 93 trimmed.

The largest buyer was Invenomic Capital Management, opening a new position worth an estimated $28.3M. The largest seller was Perceptive Advisors, cutting an estimated $48.5M.

  • 301 institutional investors held Iovance Biotherapeutics (IOVA) as of Q1 2025, unchanged from Q4 2024.
  • Funds reported $799M of Iovance Biotherapeutics stock for Q1 2025, down 55% quarter-over-quarter.
  • 56 funds opened new Iovance Biotherapeutics positions in Q1 2025 and 54 closed out, a net change of +2 holders.
  • The largest Iovance Biotherapeutics buyer in Q1 2025 was Invenomic Capital Management, an estimated $28.3M added.
  • The largest Iovance Biotherapeutics seller in Q1 2025 was Perceptive Advisors, an estimated $48.5M sold.

Based on aggregated 13F filings for Q1 2025.