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Iovance Biotherapeutics

301 hedge funds and large institutions have $799M invested in Iovance Biotherapeutics in 2025 Q1 according to their latest regulatory filings, with 56 funds opening new positions, 100 increasing their positions, 93 reducing their positions, and 54 closing their positions.

New
Increased
Maintained
Reduced
Closed

25% more call options, than puts

Call options by funds: $8.21M | Put options by funds: $6.57M

8% more repeat investments, than reductions

Existing positions increased: 100 | Existing positions reduced: 93

4% more first-time investments, than exits

New positions opened: 56 | Existing positions closed: 54

0% more funds holding

Funds holding: 301301 (0)

6.13% less ownership

Funds ownership: 79.26%73.13% (-6.1%)

55% less capital invested

Capital invested by funds: $1.79B → $799M (-$989M)

71% less funds holding in top 10

Funds holding in top 10: 72 (-5)

Holders
301
Holders Change
Holders Change %
0%
% of All Funds
4.04%
Holding in Top 10
2
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-71.43%
% of All Funds
0.03%
New
56
Increased
100
Reduced
93
Closed
54
Calls
$8.21M
Puts
$6.57M
Net Calls
+$1.64M
Net Calls Change
+$9.18M
Name Holding Trade Value Shares
Change
Change in
Stake
Citigroup
51
Citigroup
New York
$1.79M +$280K +54,270 +11%
Schroder Investment Management Group
52
Schroder Investment Management Group
United Kingdom
$1.79M +$1.34M +259,267 +107%
Royal Bank of Canada
53
Royal Bank of Canada
Ontario, Canada
$1.74M +$1.66M +322,680 +161%
CM
54
CM Management
Florida
$1.67M +$1.03M +200,000 +67%
Group One Trading
55
Group One Trading
Illinois
$1.58M -$6.29M -1,220,500 -72%
Rafferty Asset Management
56
Rafferty Asset Management
New York
$1.4M -$684K -132,612 -24%
SEI Investments
57
SEI Investments
Pennsylvania
$1.4M -$296K -57,374 -12%
Swiss National Bank
58
Swiss National Bank
Switzerland
$1.38M -$23.2K -4,500 -1%
Squarepoint
59
Squarepoint
New York
$1.33M +$1.27M +245,687 +161%
Two Sigma Investments
60
Two Sigma Investments
New York
$1.32M +$2.05M +396,994 New
RhumbLine Advisers
61
RhumbLine Advisers
Massachusetts
$1.3M +$17.6K +3,411 +0.9%
LPL Financial
62
LPL Financial
California
$1.25M +$648K +125,689 +50%
HWAM
63
Hennion & Walsh Asset Management
New Jersey
$1.22M +$159K +30,794 +9%
HF
64
HRT Financial
New York
$1.2M +$1.86M +360,742 New
Invesco
65
Invesco
Georgia
$1.11M +$579K +112,329 +51%
Raymond James Financial
66
Raymond James Financial
Florida
$1.06M -$6.41M -1,243,816 -80%
AG
67
Algert Global
California
$935K +$1.16M +224,482 +398%
Manulife (Manufacturers Life Insurance)
68
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$905K -$40.2K -7,801 -3%
AllianceBernstein
69
AllianceBernstein
Tennessee
$877K -$2.59M -501,909 -66%
Norges Bank
70
Norges Bank
Norway
$866K -$805K -156,089 -38%
CF
71
Cantor Fitzgerald
New York
$849K +$1.31M +254,879 New
Legal & General Group
72
Legal & General Group
United Kingdom
$774K -$851 -165 -0.1%
State of Wisconsin Investment Board
73
State of Wisconsin Investment Board
Wisconsin
$735K -$31.3K -6,075 -3%
Balyasny Asset Management
74
Balyasny Asset Management
Illinois
$699K -$13.5M -2,609,858 -93%
IIM
75
INTECH Investment Management
Florida
$690K +$309K +59,850 +41%

IOVA Hedge Fund Activity: Q1 2025 in Review

301 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Iovance Biotherapeutics (IOVA) for Q1 2025, worth a combined $799M — down 55% from $1.79B a quarter earlier.

Buyers outnumbered sellers: 56 funds opened new IOVA positions and 54 closed out — a net gain of 2 holders — while 100 added to existing stakes and 93 trimmed.

The largest buyer was Invenomic Capital Management, opening a new position worth an estimated $28.3M. The largest seller was Perceptive Advisors, cutting an estimated $48.5M.

  • 301 institutional investors held Iovance Biotherapeutics (IOVA) as of Q1 2025, unchanged from Q4 2024.
  • Funds reported $799M of Iovance Biotherapeutics stock for Q1 2025, down 55% quarter-over-quarter.
  • 56 funds opened new Iovance Biotherapeutics positions in Q1 2025 and 54 closed out, a net change of +2 holders.
  • The largest Iovance Biotherapeutics buyer in Q1 2025 was Invenomic Capital Management, an estimated $28.3M added.
  • The largest Iovance Biotherapeutics seller in Q1 2025 was Perceptive Advisors, an estimated $48.5M sold.

Based on aggregated 13F filings for Q1 2025.