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Gyre Therapeutics
GYRE

48 hedge funds and large institutions have $23.1M invested in Gyre Therapeutics in 2025 Q3 according to their latest regulatory filings, with 10 funds opening new positions, 13 increasing their positions, 16 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

0% more funds holding

Funds holding: 48 → 48 (0)

0% more first-time investments, than exits

New positions opened: 10 | Existing positions closed: 10

0.42% less ownership

Funds ownership: 3.64% → 3.21% (-0.42%)

8% less capital invested

Capital invested by funds: $25.1M → $23.1M (-$1.97M)

19% less repeat investments, than reductions

Existing positions increased: 13 | Existing positions reduced: 16

Holders
48
Holders Change
–
Holders Change %
0%
% of All Funds
0.63%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
10
Increased
13
Reduced
16
Closed
10
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$271K
2
Goldman Sachs
Goldman Sachs
New York
+$137K
3
Lazard Asset Management
Lazard Asset Management
New York
+$113K
4
UBS Group
UBS Group
Switzerland
+$109K
5
Jane Street
Jane Street
New York
+$98.4K

Top Sellers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
-$1.39M
2
SS
SBI Securities
Japan
-$489K
3
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$264K
4
Geode Capital Management
Geode Capital Management
Massachusetts
-$206K
5
Northern Trust
Northern Trust
Illinois
-$205K
Name Holding Trade Value Shares
Change 		Change in
Stake
Mirae Asset Global ETFs Holdings
26
Mirae Asset Global ETFs Holdings
Hong Kong
$31.4K -$24.4K -3,210 -43%
JP Morgan Chase
27
JP Morgan Chase
New York
$27.6K -$21K -2,767 -43%
New York State Common Retirement Fund
28
New York State Common Retirement Fund
New York
$20.1K – – –
TRCT
29
Tower Research Capital (TRC)
New York
$20.1K +$4.33K +570 +27%
BNP Paribas Financial Markets
30
BNP Paribas Financial Markets
France
$16.1K +$6.58K +867 +67%
PFSRSONJ
31
Police & Firemen's Retirement System of New Jersey
New Jersey
$15.6K – – –
Russell Investments Group
32
Russell Investments Group
United Kingdom
$8.38K +$8.54K +1,124 New
Legal & General Group
33
Legal & General Group
United Kingdom
$6.44K -$4.96K -653 -43%
California State Teachers Retirement System (CalSTRS)
34
California State Teachers Retirement System (CalSTRS)
California
$6.33K +$8 +1 +0.1%
AIP
35
Ameritas Investment Partners
Nebraska
$5.09K – – –
AWM
36
Activest Wealth Management
Florida
$3.98K – – –
Citigroup
37
Citigroup
New York
$2.86K -$42.2K -5,553 -94%
AB
38
Amalgamated Bank
New York
$2K – – –
Optiver Holding
39
Optiver Holding
Netherlands
$1.66K +$1.69K +222 New
Simplex Trading
40
Simplex Trading
Illinois
$1K +$1.25K +164 New
Nisa Investment Advisors
41
Nisa Investment Advisors
Missouri
$761 +$326 +43 +73%
PS
42
Principal Securities
Iowa
$634 – – –
ASN
43
Advisory Services Network
Georgia
$492 +$501 +66 New
AAP
44
Arax Advisory Partners
Colorado
$426 +$433 +57 New
Osaic Holdings
45
Osaic Holdings
Arizona
$283 – – –
SCM
46
Sterling Capital Management
North Carolina
$164 -$84 -11 -33%
Susquehanna International Group
47
Susquehanna International Group
Pennsylvania
– -$264K -35,912 Closed
N
48
Nuveen
North Carolina
– -$129K -17,594 Closed
Verition Fund Management
49
Verition Fund Management
Connecticut
– -$98.1K -13,345 Closed
American Century Companies
50
American Century Companies
Missouri
– -$83K -11,291 Closed
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GYRE Hedge Fund Activity: Q3 2025 in Review

48 of the 7,626 institutional investors tracked by Wall St. Rank reported a position in Gyre Therapeutics (GYRE) for Q3 2025, worth a combined $23.1M — down 7.9% from $25.1M a quarter earlier.

Fund positioning in GYRE was balanced in Q3 2025: 10 funds opened new positions, 10 closed out, 13 added to existing stakes and 16 trimmed.

The largest buyer was Millennium Management, opening a new position worth an estimated $271K. The largest seller was BlackRock, cutting an estimated $1.39M.

  • 48 institutional investors held Gyre Therapeutics (GYRE) as of Q3 2025, unchanged from Q2 2025.
  • Funds reported $23.1M of Gyre Therapeutics stock for Q3 2025, down 7.9% quarter-over-quarter.
  • 10 funds opened new Gyre Therapeutics positions in Q3 2025 and 10 closed out, a net change of 0 holders.
  • The largest Gyre Therapeutics buyer in Q3 2025 was Millennium Management, an estimated $271K added.
  • The largest Gyre Therapeutics seller in Q3 2025 was BlackRock, an estimated $1.39M sold.

Based on aggregated 13F filings for Q3 2025.