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Gyre Therapeutics

48 hedge funds and large institutions have $25.1M invested in Gyre Therapeutics in 2025 Q2 according to their latest regulatory filings, with 10 funds opening new positions, 25 increasing their positions, 8 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

213% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 8

25% more first-time investments, than exits

New positions opened: 10 | Existing positions closed: 8

24% more capital invested

Capital invested by funds: $20.1M → $25.1M (+$4.92M)

4% more funds holding

Funds holding: 4648 (+2)

0.6% more ownership

Funds ownership: 3.04%3.64% (+0.6%)

Holders
48
Holders Change
+2
Holders Change %
+4.35%
% of All Funds
0.63%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
10
Increased
25
Reduced
8
Closed
8
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$8.45M +$464K +53,221 +5%
BlackRock
2
BlackRock
New York
$6.19M +$2.58M +295,399 +54%
Geode Capital Management
3
Geode Capital Management
Massachusetts
$2.95M +$780K +89,390 +29%
SS
4
SBI Securities
Japan
$1.71M +$948K +108,670 +88%
State Street
5
State Street
Massachusetts
$1.31M +$427K +48,995 +38%
Northern Trust
6
Northern Trust
Illinois
$1.05M +$308K +35,319 +33%
Charles Schwab
7
Charles Schwab
California
$951K +$157K +18,004 +16%
State of Wisconsin Investment Board
8
State of Wisconsin Investment Board
Wisconsin
$277K +$329K +37,670 New
Susquehanna International Group
9
Susquehanna International Group
Pennsylvania
$264K +$166K +18,981 +112%
Morgan Stanley
10
Morgan Stanley
New York
$259K +$185K +21,228 +151%
Barclays
11
Barclays
United Kingdom
$176K +$136K +15,553 +184%
Bank of New York Mellon
12
Bank of New York Mellon
New York
$176K +$65.4K +7,497 +45%
AllianceBernstein
13
AllianceBernstein
Tennessee
$146K +$174K +19,930 New
N
14
Nuveen
North Carolina
$129K +$154K +17,594 New
RhumbLine Advisers
15
RhumbLine Advisers
Massachusetts
$119K +$44K +5,045 +45%
Verition Fund Management
16
Verition Fund Management
Connecticut
$98.1K +$116K +13,345 New
SO
17
STRS Ohio
Ohio
$97.8K +$116K +13,300 New
American Century Companies
18
American Century Companies
Missouri
$83K -$109K -12,534 -53%
Deutsche Bank
19
Deutsche Bank
Germany
$80.3K +$95.3K +10,927 New
Fidelity Investments
20
Fidelity Investments
Massachusetts
$80.1K +$91.7K +10,516 +2,797%
UBS Group
21
UBS Group
Switzerland
$63.5K -$137K -15,667 -64%
Mirae Asset Global ETFs Holdings
22
Mirae Asset Global ETFs Holdings
Hong Kong
$54.5K +$28.3K +3,244 +78%
Wells Fargo
23
Wells Fargo
California
$51.6K +$25.4K +2,907 +71%
JP Morgan Chase
24
JP Morgan Chase
New York
$47.5K +$25.8K +2,961 +85%
Bank of America
25
Bank of America
North Carolina
$46.1K +$12.2K +1,402 +29%

GYRE Hedge Fund Activity: Q2 2025 in Review

48 of the 7,599 institutional investors tracked by Wall St. Rank reported a position in Gyre Therapeutics (GYRE) for Q2 2025, worth a combined $25.1M — up 24% from $20.1M a quarter earlier.

Buyers outnumbered sellers: 10 funds opened new GYRE positions and 8 closed out — a net gain of 2 holders — while 25 added to existing stakes and 8 trimmed.

The largest buyer was BlackRock, adding an estimated $2.58M. The largest seller was UBS Group, cutting an estimated $137K.

  • 48 institutional investors held Gyre Therapeutics (GYRE) as of Q2 2025, up from 46 in Q1 2025.
  • Funds reported $25.1M of Gyre Therapeutics stock for Q2 2025, up 24% quarter-over-quarter.
  • 10 funds opened new Gyre Therapeutics positions in Q2 2025 and 8 closed out, a net change of +2 holders.
  • The largest Gyre Therapeutics buyer in Q2 2025 was BlackRock, an estimated $2.58M added.
  • The largest Gyre Therapeutics seller in Q2 2025 was UBS Group, an estimated $137K sold.

Based on aggregated 13F filings for Q2 2025.