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Gyre Therapeutics

51 hedge funds and large institutions have $13.7M invested in Gyre Therapeutics in 2021 Q4 according to their latest regulatory filings, with 12 funds opening new positions, 11 increasing their positions, 15 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

1.43% less ownership

Funds ownership: 7.81%6.39% (-1.4%)

22% less funds holding

Funds holding: 6551 (-14)

27% less repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 15

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

54% less first-time investments, than exits

New positions opened: 12 | Existing positions closed: 26

82% less capital invested

Capital invested by funds: $75.5M → $13.7M (-$61.8M)

Holders
51
Holders Change
-14
Holders Change %
-21.54%
% of All Funds
0.78%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
12
Increased
11
Reduced
15
Closed
26
Calls
$435K
Puts
Net Calls
+$435K
Net Calls Change
-$4.59M
Name Holding Trade Value Shares
Change
Change in
Stake
NCM
1
Nantahala Capital Management
Connecticut
$2.52M +$751K +43,926 +14%
Renaissance Technologies
2
Renaissance Technologies
New York
$1.62M +$3.95M +230,949 +4,353%
O
3
OrbiMed
New York
$1.58M -$2.24M -130,960 -36%
Vanguard Group
4
Vanguard Group
Pennsylvania
$1.27M -$68.1K -3,982 -2%
SM
5
Sabby Management
Florida
$1.04M +$2.35M +137,679 +977%
Millennium Management
6
Millennium Management
New York
$831K +$543K +31,735 +35%
Morgan Stanley
7
Morgan Stanley
New York
$470K +$994K +58,153 +559%
Assenagon Asset Management
8
Assenagon Asset Management
Luxembourg
$469K +$1.17M +68,352 New
Dimensional Fund Advisors
9
Dimensional Fund Advisors
Texas
$450K -$704K -41,166 -39%
IC
10
Ikarian Capital
Texas
$416K
PVI
11
Pura Vida Investments
New York
$326K -$36K -2,104 -4%
Two Sigma Investments
12
Two Sigma Investments
New York
$282K +$580K +33,931 +471%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$261K -$148K -8,661 -18%
BlackRock
14
BlackRock
New York
$235K -$30.6K -1,791 -5%
Goldman Sachs
15
Goldman Sachs
New York
$220K +$182K +10,654 +50%
Acadian Asset Management
16
Acadian Asset Management
Massachusetts
$211K +$530K +30,987 New
Two Sigma Advisers
17
Two Sigma Advisers
New York
$166K +$171K +10,013 +70%
GTCM
18
Gyon Technologies Capital Management
New Jersey
$143K +$357K +20,873 New
D.E. Shaw & Co
19
D.E. Shaw & Co
New York
$128K +$320K +18,691 New
RC
20
RBF Capital
California
$121K
KCM
21
Kynam Capital Management
New Jersey
$101K +$253K +14,799 New
Northern Trust
22
Northern Trust
Illinois
$93K -$2.77K -162 -1%
CL
23
CSS LLC
Illinois
$81K +$126K +7,348 +164%
EWM
24
Essex Woodlands Management
Texas
$72K
Bank of New York Mellon
25
Bank of New York Mellon
New York
$69K

GYRE Hedge Fund Activity: Q4 2021 in Review

51 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Gyre Therapeutics (GYRE) for Q4 2021, worth a combined $13.7M — down 82% from $75.5M a quarter earlier.

Sellers outnumbered buyers: 26 funds closed out of GYRE and 12 opened new positions — a net loss of 14 holders — while 15 trimmed existing stakes and 11 added.

The largest buyer was Renaissance Technologies, adding an estimated $3.95M. The largest seller was Stonepine Capital Management, exiting entirely with an estimated $10.8M sold.

  • 51 institutional investors held Gyre Therapeutics (GYRE) as of Q4 2021, down from 65 in Q3 2021.
  • Funds reported $13.7M of Gyre Therapeutics stock for Q4 2021, down 82% quarter-over-quarter.
  • 12 funds opened new Gyre Therapeutics positions in Q4 2021 and 26 closed out, a net change of -14 holders.
  • The largest Gyre Therapeutics buyer in Q4 2021 was Renaissance Technologies, an estimated $3.95M added.
  • The largest Gyre Therapeutics seller in Q4 2021 was Stonepine Capital Management, an estimated $10.8M sold.

Based on aggregated 13F filings for Q4 2021.