Jane Street
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Jane Street’s Gyre Therapeutics GYRE Stock Holding History

Jane Street’s Portfolio GYRE Stock Details GYRE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-12,958
Closed -$100K – 11634
2025
Q3 		$96.7K Buy
+12,958
New +$98.4K ﹤0.01% 10149
2024
Q2 		– Sell
-30,555
Closed -$534K – 9703
2024
Q1 		$534K Buy
+30,555
New +$551K ﹤0.01% 6551
2023
Q1 		– Sell
-4,174
Closed -$16.5K – 9375
2022
Q4 		$16.5K Buy
+4,174
New +$17K ﹤0.01% 8649
2022
Q1 		– Sell
-2,317
Closed -$16K – 10577
2021
Q4 		$16K Buy
+2,317
New +$39.6K ﹤0.01% 9839
2021
Q2 		– Sell
-1,537
Closed -$58K – 10007
2021
Q1 		$58K Buy
+1,537
New +$70.3K ﹤0.01% 8805
2020
Q4 		– Sell
-4,904
Closed -$158K – 7723
2020
Q3 		$158K Buy
4,904
+2,560
+109% +$100K ﹤0.01% 6567
2020
Q2 		$103K Buy
+2,344
New +$110K ﹤0.01% 6693
2019
Q3 		– Sell
-1,938
Closed -$107K – 5337
2019
Q2 		$107K Buy
+1,938
New +$121K ﹤0.01% 4844
2014
Q4 		– Sell
-15
Closed -$29K – 2684
2014
Q3 		$29K Buy
+15
New +$37.1K ﹤0.01% 2450
2013
Q3 		– Sell
-16
Closed -$53K – 2866
2013
Q2 		$53K Buy
+16
New +$60.9K ﹤0.01% 2530

Other funds holding GYRE

VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
SS
SBI Securities Tokyo, Japan $3.65B AUM 41.88% 1-Year Est. Return
Charles Schwab
Charles Schwab San Francisco, California $654B AUM 26.35% 1-Year Est. Return
VFT
Vanguard Fiduciary Trust Malvern, Pennsylvania $396B AUM
Northern Trust
Northern Trust Chicago, Illinois $757B AUM 28.64% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

Jane Street's GYRE Position: Q4 2025 in Review

Jane Street sold out of Gyre Therapeutics (GYRE) in Q4 2025, closing a stake of 12,958 shares — an estimated $100K sold.

Jane Street first reported a position in GYRE in Q2 2013 and held it in 10 quarters. The position peaked at $534K in Q1 2024. 44 funds tracked by Wall St. Rank hold GYRE as of Q4 2025.

  • Jane Street reported no remaining Gyre Therapeutics position as of Q4 2025 after selling out during the quarter.
  • Jane Street sold 12,958 Gyre Therapeutics shares in Q4 2025, an estimated $100K.
  • Jane Street first reported a position in Gyre Therapeutics in Q2 2013 and held it in 10 quarters.
  • Jane Street's Gyre Therapeutics position peaked at $534K in Q1 2024.
  • 44 funds tracked by Wall St. Rank held Gyre Therapeutics as of Q4 2025.

Based on Jane Street's 13F filing for Q4 2025, filed 12 Feb 2026.