|
1
|
Wellington Management Group
Boston,
Massachusetts
|
$250M
|
+$61.4M
|
+1,455,330
|
+33%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$126M
|
-$45.8M
|
-1,085,820
|
-27%
|
|
|
3
|
Driehaus Capital Management
Chicago,
Illinois
|
$107M
|
-$4.59M
|
-108,776
|
-4%
|
|
|
4
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$96.7M
|
-$422K
|
-10,000
|
-0.4%
|
|
|
5
|
Janus Henderson Group
London,
|
$89M
|
+$22.4M
|
+532,284
|
+34%
|
|
|
6
|
TCG Crossover Management
Palo Alto,
California
|
$68.5M
|
-$21.6M
|
-511,163
|
-24%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$66.9M
|
-$5M
|
-118,486
|
-7%
|
|
|
8
|
Capital Research Global Investors
Los Angeles,
California
|
$65.5M
|
+$23.4M
|
+553,948
|
+57%
|
|
|
9
|
RA Capital Management
Boston,
Massachusetts
|
$64.7M
|
+$43.2M
|
+1,023,530
|
+210%
|
|
|
10
|
Alyeska Investment Group
Chicago,
Illinois
|
$55.8M
|
+$47.3M
|
+1,122,309
|
+628%
|
|
|
11
|
Capital International Investors
Los Angeles,
California
|
$54.9M
|
+$18.2M
|
+431,540
|
+51%
|
|
|
12
|
Citadel Advisors
Miami,
Florida
|
$54.7M
|
+$5.18M
|
+122,877
|
+11%
|
|
|
13
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$52.1M
|
-$4.04M
|
-95,892
|
-7%
|
|
|
14
|
|
$47.9M
|
+$1.05M
|
+25,000
|
+2%
|
|
|
15
|
|
$46.6M
|
+$1.07M
|
+25,355
|
+2%
|
|
|
16
|
Deerfield Management
New York
|
$44.3M
|
+$8.89M
|
+210,867
|
+26%
|
|
|
17
|
HSG Holding
Na,
Hong Kong
|
$38.4M
|
-$10.3K
|
-244
|
-0%
|
|
|
18
|
Avidity Partners Management
Dallas,
Texas
|
$37M
|
-$9.11M
|
-216,000
|
-20%
|
|
|
19
|
BVF Inc
San Francisco,
California
|
$34.8M
|
–
|
–
|
–
|
|
|
20
|
Adage Capital Partners
Boston,
Massachusetts
|
$34.7M
|
-$39.9M
|
-946,316
|
-54%
|
|
|
21
|
Logos Global Management
San Francisco,
California
|
$30.9M
|
-$14.8M
|
-350,000
|
-33%
|
|
|
22
|
Capital World Investors
Los Angeles,
California
|
$27.2M
|
–
|
–
|
–
|
|
|
23
|
Frazier Life Sciences Management
Palo Alto,
California
|
$27M
|
+$13.2M
|
+312,004
|
+98%
|
|
|
24
|
Franklin Resources
San Mateo,
California
|
$23M
|
-$277K
|
-6,576
|
-1%
|
|
|
25
|
Octagon Capital Advisors
New York
|
$21.7M
|
+$3.9M
|
+92,604
|
+22%
|
|
