|
1
|
Wellington Management Group
Boston,
Massachusetts
|
$178M
|
+$201M
|
+3,504,747
|
+404%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$164M
|
+$140M
|
+2,444,249
|
+154%
|
|
|
3
|
Driehaus Capital Management
Chicago,
Illinois
|
$106M
|
+$12M
|
+210,203
|
+9%
|
|
|
4
|
Avoro Capital Advisors
New York
|
$95.1M
|
+$76.4M
|
+1,333,333
|
+133%
|
|
|
5
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$92.4M
|
+$66.3M
|
+1,157,006
|
+104%
|
|
|
6
|
TCG Crossover Management
Palo Alto,
California
|
$86M
|
+$34.8M
|
+606,837
|
+40%
|
|
|
7
|
Adage Capital Partners
Boston,
Massachusetts
|
$71.6M
|
-$2.46M
|
-43,005
|
-2%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$68.5M
|
-$47.8M
|
-834,127
|
-33%
|
|
|
9
|
Janus Henderson Group
London,
|
$62.8M
|
-$31.3M
|
-546,907
|
-26%
|
|
|
10
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$53.5M
|
-$14.9M
|
-259,482
|
-17%
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$47M
|
+$4.15M
|
+72,393
|
+7%
|
|
|
12
|
|
$44.5M
|
-$9.53M
|
-166,299
|
-13%
|
|
|
13
|
HSG Holding
Na,
Hong Kong
|
$44.1M
|
–
|
–
|
–
|
|
|
14
|
Avidity Partners Management
Dallas,
Texas
|
$44M
|
+$33.2M
|
+580,000
|
+116%
|
|
|
15
|
Logos Global Management
San Francisco,
California
|
$43.6M
|
+$32.7M
|
+570,058
|
+114%
|
|
|
16
|
|
$43.2M
|
+$30.6M
|
+533,728
|
+101%
|
|
|
17
|
Capital Research Global Investors
Los Angeles,
California
|
$39.7M
|
+$36M
|
+628,687
|
+182%
|
|
|
18
|
Capital International Investors
Los Angeles,
California
|
$34.6M
|
+$48.7M
|
+850,024
|
New
|
|
|
19
|
Deerfield Management
New York
|
$33.5M
|
+$11.2M
|
+195,000
|
+31%
|
|
|
20
|
BVF Inc
San Francisco,
California
|
$33.1M
|
-$53.7M
|
-937,012
|
-54%
|
|
|
21
|
Capital World Investors
Los Angeles,
California
|
$25.8M
|
+$30.6M
|
+533,760
|
+532%
|
|
|
22
|
Franklin Resources
San Mateo,
California
|
$22.1M
|
+$16.7M
|
+291,503
|
+116%
|
|
|
23
|
RA Capital Management
Boston,
Massachusetts
|
$19.8M
|
+$27.9M
|
+486,832
|
New
|
|
|
24
|
|
$17.4M
|
+$20.4M
|
+356,302
|
+499%
|
|
|
25
|
Octagon Capital Advisors
New York
|
$16.9M
|
+$23.7M
|
+414,000
|
New
|
|
