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GOSS

Name Holding Trade Value Shares
Change 		Change in
Stake
NMC
1
NEA Management Company
Maryland
$13.1M +$14.1M +12,260,536 +354%
Vanguard Group
2
Vanguard Group
Pennsylvania
$9.38M +$8.86M +7,686,213 +215%
EC
3
EcoR1 Capital
California
$7.66M +$10.6M +9,195,404 New
OCA
4
Octagon Capital Advisors
New York
$6.82M +$4.87M +4,229,814 +107%
AVM
5
Arch Venture Management
Illinois
$6.71M +$9.28M +8,055,916 New
Millennium Management
6
Millennium Management
New York
$5.87M +$3.28M +2,844,283 +68%
Alyeska Investment Group
7
Alyeska Investment Group
Illinois
$5.67M +$7.84M +6,803,500 New
PAI
8
Palo Alto Investors
California
$5.44M +$3.53M +3,065,136 +88%
BC
9
Boxer Capital
California
$5.41M +$3.64M +3,160,772 +95%
AG
10
Artal Group
Luxembourg
$5.33M +$3.89M +3,371,648 +111%
GPP
11
Great Point Partners
Connecticut
$5.19M +$7.18M +6,230,272 New
Citadel Advisors
12
Citadel Advisors
Florida
$5.14M +$5.46M +4,741,674 +332%
FCM
13
Farallon Capital Management
California
$5.11M +$7.06M +6,130,272 New
MAP
14
Madison Avenue Partners
New York
$5.11M +$7.06M +6,130,268 New
SB
15
Samsara BioCapital
California
$5.11M +$7.06M +6,130,268 New
SCM
16
Silverarc Capital Management
Massachusetts
$5.11M +$7.06M +6,130,268 New
NCM
17
Nantahala Capital Management
Connecticut
$5.07M +$7.02M +6,089,471 New
PIM
18
Platinum Investment Management
Australia
$4.46M +$3.45M +2,994,608 +127%
MIM
19
Monashee Investment Management
Massachusetts
$4.42M +$6.11M +5,304,212 New
HA
20
HHLR Advisors
Cayman Islands
$4.14M – – –
AC
21
Armistice Capital
New York
$4.13M +$5.71M +4,956,000 New
OM
22
Opaleye Management
Massachusetts
$3.96M +$1.6M +1,384,200 +41%
BlackRock
23
BlackRock
New York
$3.72M +$2.94M +2,554,648 +134%
EP
24
Eversept Partners
New York
$3.69M +$4.24M +3,678,160 +491%
Federated Hermes
25
Federated Hermes
Pennsylvania
$3.33M +$3.52M +3,057,419 +326%
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