|
1
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$88.9M
|
–
|
–
|
–
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$88M
|
+$18.5M
|
+1,493,836
|
+26%
|
|
|
3
|
|
$66M
|
+$4.25M
|
+342,213
|
+7%
|
|
|
4
|
EcoR1 Capital
San Francisco,
California
|
$49.8M
|
+$51.6M
|
+4,160,887
|
New
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$45.3M
|
-$1.21M
|
-97,291
|
-3%
|
|
|
6
|
Boxer Capital
San Diego,
California
|
$42.8M
|
+$13.8M
|
+1,109,570
|
+45%
|
|
|
7
|
NEA Management Company
Timonium,
Maryland
|
$41.5M
|
+$43M
|
+3,467,406
|
New
|
|
|
8
|
|
$38.9M
|
+$11M
|
+887,656
|
+38%
|
|
|
9
|
Cormorant Asset Management
Boston,
Massachusetts
|
$38.3M
|
+$37.2M
|
+3,000,000
|
+1,512%
|
|
|
10
|
Weiss Asset Management
Boston,
Massachusetts
|
$33.2M
|
+$34.4M
|
+2,773,924
|
New
|
|
|
11
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$26.3M
|
-$16.5M
|
-1,328,163
|
-38%
|
|
|
12
|
Octagon Capital Advisors
New York
|
$24.5M
|
-$8.85M
|
-712,627
|
-26%
|
|
|
13
|
Palo Alto Investors
Palo Alto,
California
|
$21M
|
–
|
–
|
–
|
|
|
14
|
|
$20.9M
|
+$21.7M
|
+1,747,000
|
New
|
|
|
15
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$19M
|
+$19.7M
|
+1,586,962
|
New
|
|
|
16
|
Omega Fund Management
Boston,
Massachusetts
|
$18M
|
–
|
–
|
–
|
|
|
17
|
Avidity Partners Management
Dallas,
Texas
|
$17.4M
|
+$18M
|
+1,450,000
|
New
|
|
|
18
|
Madison Avenue Partners
New York
|
$16.6M
|
+$17.2M
|
+1,386,962
|
New
|
|
|
19
|
Millennium Management
New York
|
$15.9M
|
-$1.88M
|
-151,590
|
-10%
|
|
|
20
|
Fidelity Investments
Boston,
Massachusetts
|
$15.4M
|
+$4.17M
|
+335,700
|
+35%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$15.1M
|
+$2.89M
|
+232,714
|
+23%
|
|
|
22
|
|
$14.5M
|
-$2.11M
|
-169,661
|
-12%
|
|
|
23
|
|
$12.9M
|
+$2.49M
|
+200,311
|
+23%
|
|
|
24
|
|
$12.6M
|
+$5.1M
|
+410,923
|
+64%
|
|
|
25
|
|
$11.7M
|
+$11.4M
|
+916,979
|
+1,554%
|
|
